Multimodal modeling of neural network activity: computing LFP, ECoG, EEG, and MEG signals with LFPy 2.0

E Hagen, S Næss, TV Ness… - Frontiers in …, 2018 - frontiersin.org
Recordings of extracellular electrical, and later also magnetic, brain signals have been the
dominant technique for measuring brain activity for decades. The interpretation of such …

Biophysical psychiatry—how computational neuroscience can help to understand the complex mechanisms of mental disorders

T Mäki-Marttunen, T Kaufmann, T Elvsåshagen… - Frontiers in …, 2019 - frontiersin.org
The brain is the most complex of human organs, and the pathophysiology underlying
abnormal brain function in psychiatric disorders is largely unknown. Despite the rapid …

In-silico EEG biomarkers of reduced inhibition in human cortical microcircuits in depression

F Mazza, A Guet-McCreight, TA Valiante… - PLoS Computational …, 2023 - journals.plos.org
Reduced cortical inhibition by somatostatin-expressing (SST) interneurons has been
strongly associated with treatment-resistant depression. However, due to technical …

Methods for inferring neural circuit interactions and neuromodulation from local field potential and electroencephalogram measures

P Martínez-Cañada, S Noei, S Panzeri - Brain Informatics, 2021 - Springer
Electrical recordings of neural mass activity, such as local field potentials (LFPs) and
electroencephalograms (EEGs), have been instrumental in studying brain function …

Alterations in schizophrenia-associated genes can lead to increased power in delta oscillations

T Mäki-Marttunen, F Krull, F Bettella, E Hagen… - Cerebral …, 2019 - academic.oup.com
Genome-wide association studies have implicated many ion channels in schizophrenia
pathophysiology. Although the functions of these channels are relatively well characterized …

Computation of the electroencephalogram (EEG) from network models of point neurons

P Martínez-Cañada, TV Ness, GT Einevoll… - PLOS Computational …, 2021 - journals.plos.org
The electroencephalogram (EEG) is a major tool for non-invasively studying brain function
and dysfunction. Comparing experimentally recorded EEGs with neural network models is …

Neurobiologically realistic neural network enables cross-scale modeling of neural dynamics

YJ Chang, YI Chen, HC Yeh, SR Santacruz - Scientific Reports, 2024 - nature.com
Fundamental principles underlying computation in multi-scale brain networks illustrate how
multiple brain areas and their coordinated activity give rise to complex cognitive functions …

Conservative finite element modeling of EEG and MEG on unstructured grids

N Yavich, N Koshev, M Malovichko… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
For interpretation of electroencephalography (EEG) and magnetoencephalography (MEG)
data, multiple solutions of the respective forward problems are needed. In this paper, we …

Forward model of rat electroencephalogram: comparative study of numerical simulations with measurements on rat head phantoms

D Kuratko, J Lacik, V Koudelka, C Vejmola… - IEEE …, 2022 - ieeexplore.ieee.org
In the paper, we propose a procedure to be used for the validation of software for forward
modeling of rat electroencephalogram with scalp potentials measured on rat head …

Simulating epileptic seizures using the bidomain model

J Schreiner, KA Mardal - Scientific Reports, 2022 - nature.com
Epileptic seizures are due to excessive and synchronous neural activity. Extensive
modelling of seizures has been done on the neuronal level, but it remains a challenge to …