What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus
What can be expected in normal aging, and where does normal aging stop and pathological
neurodegeneration begin? With the slow progression of age-related dementias such as …
neurodegeneration begin? With the slow progression of age-related dementias such as …
Injured brains and adaptive networks: the benefits and costs of hyperconnectivity
FG Hillary, JH Grafman - Trends in cognitive sciences, 2017 - cell.com
A common finding in human functional brain-imaging studies is that damage to neural
systems paradoxically results in enhanced functional connectivity between network regions …
systems paradoxically results in enhanced functional connectivity between network regions …
Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease
Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's
disease, but the functional brain mechanisms that support cognitive resilience remain …
disease, but the functional brain mechanisms that support cognitive resilience remain …
The impact of bilingualism on brain reserve and metabolic connectivity in Alzheimer's dementia
Cognitive reserve (CR) prevents cognitive decline and delays neurodegeneration. Recent
epidemiological evidence suggests that lifelong bilingualism may act as CR delaying the …
epidemiological evidence suggests that lifelong bilingualism may act as CR delaying the …
Synaptic plasticity shapes brain connectivity: implications for network topology
M Stampanoni Bassi, E Iezzi, L Gilio… - International journal of …, 2019 - mdpi.com
Studies of brain network connectivity improved understanding on brain changes and
adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to …
adaptation in response to different pathologies. Synaptic plasticity, the ability of neurons to …
Four distinct subtypes of Alzheimer's disease based on resting-state connectivity biomarkers
Background Alzheimer's disease (AD) is a neurodegenerative disorder with significant
heterogeneity. Different AD phenotypes may be associated with specific brain network …
heterogeneity. Different AD phenotypes may be associated with specific brain network …
Educational attainment, structural brain reserve and Alzheimer's disease: a Mendelian randomization analysis
Higher educational attainment is observationally associated with lower risk of Alzheimer's
disease. However, the biological mechanisms underpinning this association remain unclear …
disease. However, the biological mechanisms underpinning this association remain unclear …
Lifelong bilingualism contributes to cognitive reserve against white matter integrity declines in aging
BT Gold, NF Johnson, DK Powell - Neuropsychologia, 2013 - Elsevier
Recent evidence suggests that lifelong bilingualism may contribute to cognitive reserve (CR)
in normal aging. However, there is currently no neuroimaging evidence to suggest that …
in normal aging. However, there is currently no neuroimaging evidence to suggest that …
Relationships between sleep quality and brain volume, metabolism, and amyloid deposition in late adulthood
P Branger, EM Arenaza-Urquijo, C Tomadesso… - Neurobiology of …, 2016 - Elsevier
Recent studies in mouse models of Alzheimer's disease (AD) and in humans suggest that
sleep disruption and amyloid-beta (Aβ) accumulation are interrelated, and may, thus …
sleep disruption and amyloid-beta (Aβ) accumulation are interrelated, and may, thus …
[HTML][HTML] The positive impacts of early-life education on cognition, leisure activity, and brain structure in healthy aging
Education in people's early lives are positively related to their cognitive function, but its
modulating effects on detailed cognition domains, its interaction with leisure activities and …
modulating effects on detailed cognition domains, its interaction with leisure activities and …