Optical biosensors for therapeutic drug monitoring

V Garzón, DG Pinacho, RH Bustos, G Garzón… - Biosensors, 2019 - mdpi.com
Therapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that
have a limited dosage or high toxicity, which could endanger the lives of patients. To carry …

Biosensors and nanobiosensors for rapid detection of autoimmune diseases: a review

F Ghorbani, H Abbaszadeh, A Mehdizadeh… - Microchimica Acta, 2019 - Springer
Abstract This review (with 77 refs.) describes the progress that has been made in biosensors
for the detection of autoimmune diseases, mainly via detection of autoantibodies. In addition …

Label-free detection of exosomes using a surface plasmon resonance biosensor

AAI Sina, R Vaidyanathan, A Wuethrich… - Analytical and …, 2019 - Springer
The development of a sensitive and specific detection platform for exosomes is highly
desirable as they are believed to transmit vital tumour-specific information (mRNAs …

Development of label-free immunoassays as novel solutions for the measurement of monoclonal antibody drugs and antidrug antibodies

YR Luo, I Chakraborty, E Lazar-Molnar… - Clinical …, 2020 - academic.oup.com
Background Immunoassays based on label-free technologies (label-free immunoassay
[LFIA]) offer an innovative approach to clinical diagnostics and demonstrate great promise …

Determination of Tyrosine Kinase Inhibitors via Capillary Electrophoresis with Tandem Mass Spectrometry and Online Stacking Preconcentration

J Petr - Pharmaceuticals, 2023 - mdpi.com
Capillary electrophoresis connected with tandem mass spectrometry was employed for the
development of a method for determination of various tyrosine kinase inhibitors in plasma …

Exosome Isolation and Detection: From Microfluidic Chips to Nanoplasmonic Biosensor

J Shen, Z Ma, J Xu, T Xue, X Lv, G Zhu… - ACS Applied Materials …, 2024 - ACS Publications
Exosomes are becoming more widely acknowledged as significant circulating indicators for
the prognosis and diagnosis of cancer. Circulating exosomes are essential to the …

Utilizing the thiol chemistry of biomolecules for the rapid determination of anti-TNF-α drug in blood

S Muneer, GA Ayoko, N Islam, EL Izake - Talanta, 2020 - Elsevier
The detection of anti-TNF-α drugs require rapid, selective and sensitive biosensors that can
be easily utilised at the point of care. Herein, we demonstrate a new biosensing approach …

Development and ELISA Characterization of Antibodies against the Colistin, Vancomycin, Daptomycin, and Meropenem: A Therapeutic Drug Monitoring Approach

V Garzon, JP Salvador, MP Marco, D G.-Pinacho… - Antibiotics, 2024 - mdpi.com
More than 70% of bacteria are resistant to all or nearly all known antimicrobials, creating the
need for the development of new types of antimicrobials or the use of “last-line” antimicrobial …

Repurposing Fc gamma receptor I (FcγRI, CD64) for site-oriented monoclonal antibody capture: A proof-of-concept study for real-time detection of tumor necrosis …

E Çapkın, A Kutlu, M Yüce - Heliyon, 2023 - cell.com
The controlled orientation of biomolecules on the sensor surface is crucial for achieving high
sensitivity and accurate detection of target molecules in biosensing. FcγRI is an immune cell …

Ultrahigh-Sensitivity Detection of TNF-α Based on U-Shape Single Mode-Tapered Four Core-Single Mode Fiber Biosensor

HY Cao, D Wei, Y Hu, B Liu, Y Fu, J Liu… - IEEE Sensors …, 2024 - ieeexplore.ieee.org
In this article, a high-sensitivity U-shape single mode-tapered four core-single mode (STFS)
optical fiber biosensor is proposed and investigated for tumor necrosis factor-alpha (TNF-) …