Neuroinflammation is a central mechanism involved in neurodegeneration as observed in
Alzheimer's disease (AD), the most prevalent form of neurodegenerative disease …

For the past three decades, apolipoprotein E (APOE) has been known as the single greatest
genetic modulator of sporadic Alzheimer disease (AD) risk, influencing both the average age …

Alzheimer's disease (AD) has complex etiologies, and the impact of sex on AD varies over
the course of disease development. The literature provides some evidence of sex-specific …

Importance For the Alzheimer disease (AD) therapies to effectively attenuate clinical
progression, it may be critical to intervene before the onset of amyloid-associated tau …

Sex characteristics exhibit significant disparities in various human diseases, including
prevalent cardiovascular diseases, cancers, metabolic disorders, autoimmune diseases …

The effects of fasting-mimicking diet (FMD) cycles in reducing many aging and disease risk
factors indicate it could affect Alzheimer's disease (AD). Here, we show that FMD cycles …

Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

The amyloid hypothesis has dominated Alzheimer's disease (AD) research for almost 30
years. This hypothesis hinges on the predominant clinical role of the amyloid beta (Aβ) …

Females show a disproportionate burden of Alzheimer's disease pathology and higher
Alzheimer's disease dementia prevalences compared to males, yet the mechanisms driving …

Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the
presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are …