Cutting through the noise: Noise-induced cochlear synaptopathy and individual differences in speech understanding among listeners with normal audiograms

M DiNino, LL Holt, BG Shinn-Cunningham - Ear and hearing, 2022 - journals.lww.com
Following a conversation in a crowded restaurant or at a lively party poses immense
perceptual challenges for some individuals with normal hearing thresholds. A number of …

[HTML][HTML] Hidden hearing loss: Fifteen years at a glance

J Liu, J Stohl, T Overath - Hearing Research, 2024 - Elsevier
Hearing loss affects approximately 18% of the population worldwide. Hearing difficulties in
noisy environments without accompanying audiometric threshold shifts likely affect an even …

Envelope following responses predict speech-in-noise performance in normal-hearing listeners

AM Mepani, S Verhulst, KE Hancock… - Journal of …, 2021 - journals.physiology.org
Permanent threshold elevation after noise exposure or aging is caused by loss of sensory
cells; however, animal studies show that hair cell loss is often preceded by degeneration of …

A neural-network framework for the design of individualised hearing-loss compensation

F Drakopoulos, S Verhulst - IEEE/ACM Transactions on Audio …, 2023 - ieeexplore.ieee.org
Sound processing in the human auditory system is complex and highly non-linear, whereas
hearing aids (HAs) still rely on simplified descriptions of auditory processing or hearing loss …

Audiological and psychological assessment of tinnitus patients with normal hearing

Y Park, SH Shin, SW Byun, ZY Lee, HY Lee - Frontiers in Neurology, 2023 - frontiersin.org
Introduction This study was performed to assess identifiable abnormalities in tinnitus
patients with normal hearing. Methods The medical records of subjective non-pulsatile …

[HTML][HTML] Age-related reduction in frequency-following responses as a potential marker of cochlear neural degeneration

J Märcher-Rørsted, G Encina-Llamas, T Dau… - Hearing Research, 2022 - Elsevier
Healthy aging may be associated with neural degeneration in the cochlea even before
clinical hearing loss emerges. Reduction in frequency-following responses (FFRs) to tonal …

Envelope following responses for hearing diagnosis: Robustness and methodological considerations

H Van Der Biest, S Keshishzadeh, H Keppler… - The Journal of the …, 2023 - pubs.aip.org
Recent studies have found that envelope following responses (EFRs) are a marker of age-
related and noise-or ototoxic-induced cochlear synaptopathy (CS) in research animals …

Predicting synapse counts in living humans by combining computational models with auditory physiology

BN Buran, GP McMillan, S Keshishzadeh… - The Journal of the …, 2022 - pubs.aip.org
Aging, noise exposure, and ototoxic medications lead to cochlear synapse loss in animal
models. As cochlear function is highly conserved across mammalian species, synaptopathy …

Towards personalized auditory models: Predicting individual sensorineural hearing-loss profiles from recorded human auditory physiology

S Keshishzadeh, M Garrett, S Verhulst - Trends in Hearing, 2021 - journals.sagepub.com
Over the past decades, different types of auditory models have been developed to study the
functioning of normal and impaired auditory processing. Several models can simulate …

Animal-to-human translation difficulties and problems with proposed coding-in-noise deficits in noise-induced synaptopathy and hidden hearing loss

S Ripley, L Xia, Z Zhang, SJ Aiken… - Frontiers in Neuroscience, 2022 - frontiersin.org
Noise induced synaptopathy (NIS) and hidden hearing loss (NIHHL) have been hot topic in
hearing research since a massive synaptic loss was identified in CBA mice after a brief …