Asymmetric catalysis plays a key role in modern synthetic organic chemistry, with synthetic
catalysts and enzymes being the two available options. During the latter part of the last …

Evolution requires the generation and optimization of new traits (“adaptation”) and involves
the selection of mutations that improve cellular function. These mutations were assumed to …

We have developed a protocol to assemble in one step and one tube at least nine separate
DNA fragments together into an acceptor vector, with 90% of recombinant clones obtained …

Our previous contribution to increasing the efficiency of directed evolution is iterative
saturation mutagenesis (ISM) as a systematic means of generating focused libraries for the …

Efficacy in laboratory evolution of enzymes is currently a pressing issue, making
comparative studies of different methods and strategies mandatory. Recent reports indicate …

Covering: up to August 2024 Enzymes play an essential role in synthesizing value-added
chemicals with high specificity and selectivity. Since enzymes utilize substrates derived from …

The statement that biocatalysis is of great importance sounds trivial in face of the fact that
biocatalysis is the prerequisite for any life at all. Application of biocatalysis has a more than …

Abstract Asymmetrische Katalyse spielt eine Schlüsselrolle in der modernen synthetischen
organischen Chemie, wobei künstliche Katalysatoren und Enzyme die zwei wichtigsten …

The mRNA display technology enables the in vitro selection and directed evolution of
functional proteins from libraries of more than 1012 different mutants in a single test tube …

Targeting of tumour‐associated antigens is an expanding treatment modality in clinical
oncology as an alternative to, or in combination with, conventional treatments, such as …