Circadian clocks are biological timing mechanisms that generate 24-h rhythms of physiology
and behavior, exemplified by cycles of sleep/wake, hormone release, and metabolism. The …

The biological clock system is an intrinsic timekeeping device that integrates internal
physiology and external cues. Maintaining a healthy biological clock system is crucial for life …

A supervised intense aerobic exercise program improves the health of individuals with
metabolic syndrome (MetS). However, it is unclear whether the timing of training within the …

The circadian rhythmicity of endogenous metabolic and hormonal processes is controlled by
a complex system of central and peripheral pacemakers, influenced by exogenous factors …

Exercise is a first-line therapy recommended for patients with type 2 diabetes (T2D).
Although moderate to vigorous exercise (eg 150 min/wk) is often advised alongside diet …

Background The 5ʹ adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a
cellular energy sensor that is activated by increases in the cellular AMP/adenosine …

The primary variables influencing the adaptive response to a bout of endurance training are
exercise duration and exercise intensity. However, altering the availability of nutrients before …

High-intensity and sprint interval training (HIIT and SIT, respectively) enhance insulin
sensitivity and glycemic control in both healthy adults and those with cardiometabolic …

Intramuscular lipid (IMCL) utilization during exercise was controversial as numerous studies
did not observe a decline in IMCL content post-exercise when assessed in muscle biopsies …

Type 2 diabetes (T2D) is a rapidly growing yet largely preventable chronic disease.
Exaggerated increases in blood glucose concentration following meals is a primary …