Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …

Proteoglycans comprise a core protein to which one or more glycosaminoglycan chains are
covalently attached. Although a small number of proteins have the capacity to be glycanated …

A recombinant severe acute respiratory syndrome coronavirus (SARS-CoV) lacking the
envelope (E) protein is attenuated in vivo. Here we report that E protein PDZ-binding motif …

Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer
characterized by aggressive local invasion and metastasis. The pathogenesis of OSCC is …

PDZ domains are highly abundant protein–protein interaction modules and are often found
in multidomain scaffold proteins. PDZ-domain-containing scaffold proteins regulate multiple …

Protein–protein interactions within protein networks shape the human interactome, which
often is promoted by specialized protein interaction modules, such as the postsynaptic …

Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

Abstract Post-synaptic density-95, disks-large and zonula occludens-1 (PDZ) domains are
small globular protein–protein interaction domains widely conserved from yeast to humans …

The high-risk Human Papillomavirus (HPV) E6 oncoproteins are characterised by the
presence of a class I PDZ-binding motif (PBM) on their extreme carboxy termini. The PBM is …

The human papillomavirus (HPV) E6 oncoprotein is fundamental to the ability of these
viruses to induce human malignancy. A defining characteristic of the HPV E6 oncoproteins …