Extracellular vesicles are shed by every cell type and can be found in any biofluid. They
contain different molecules that can be utilized as biomarkers, including several RNA …

High cancer mortality rates and the rising cancer burden worldwide drive the development of
innovative methods in order to advance cancer diagnostics. Urine contains a viable source …

The analysis of circulating tumor DNA (ctDNA) in liquid biopsy specimens has an
established role for the detection of predictive molecular alterations and acquired resistance …

Introduction Uveal melanoma is a lethal intraocular tumour, in which the presence of certain
genetic alterations correlates with the risk of metastatic dissemination and patient survival …

Early detection of malignancies, through regular cancer screening, has already proven to
have potential to increase survival rates. Yet current screening methods rely on invasive …

The potential of liquid biopsy for the prognosis and diagnosis of diseases is unquestionable.
Within the evolving landscape of disease diagnostics and personalized medicine, circulating …

Circulating tumor DNA (ctDNA) is nowadays considered a robust source to search for
druggable tumoral genetic alterations, and in some specific settings liquid biopsy (LB) is …

Background This retrospective study compares real-world performance of cerebrospinal
fluid (CSF) CNSide™ versus cytology in leptomeningeal disease (LMD). Methods …

Background Cytopathology analysis of cerebrospinal fluid (CSF) is limited in detecting
tumors in patients with suspected primary or metastatic central nervous system (CNS) …

Most of the current utilization of liquid biopsy (LBx) is based on analyzing cell-free DNA
(cfDNA). There is limited data on using cell-free RNA (cfRNA) levels (liquid transcriptome) in …