Bovine tuberculosis in cattle: vaccines, DIVA tests, and host biomarker discovery

HM Vordermeier, GJ Jones, BM Buddle… - Annual review of …, 2016 - annualreviews.org
Bovine tuberculosis remains a major economic and animal welfare concern worldwide.
Cattle vaccination is being considered as part of control strategies. This approach, used …

Challenges for controlling bovine tuberculosis in South Africa

LF Arnot, A Michel - Onderstepoort Journal of Veterinary Research, 2020 - journals.co.za
All effects taken together, bovine tuberculosis (bTB) has a long-term detrimental effect on
bovine herds and many wildlife species in South Africa. The disease is not only found in …

Oral Vaccination of Free-Living Badgers (Meles meles) with Bacille Calmette Guérin (BCG) Vaccine Confers Protection against Tuberculosis

E Gormley, D Ní Bhuachalla, J O'Keeffe, D Murphy… - PloS one, 2017 - journals.plos.org
A field trial was conducted to investigate the impact of oral vaccination of free-living badgers
against natural-transmitted Mycobacterium bovis infection. For a period of three years …

Identification of novel potential vaccine candidates against tuberculosis based on reverse vaccinology

GP Monterrubio-López… - BioMed research …, 2015 - Wiley Online Library
Tuberculosis (TB) is a chronic infectious disease, considered as the second leading cause
of death worldwide, caused by Mycobacterium tuberculosis. The limited efficacy of the …

Open questions and recent advances in the control of a multi‐host infectious disease: Animal tuberculosis

C Gortázar, A Che Amat, DJ O'Brien - Mammal review, 2015 - Wiley Online Library
Animal tuberculosis (TB) control is globally important for public health, economics and
conservation. Wildlife species are often part of the M ycobacterium tuberculosis complex …

Animal models of tuberculosis vaccine research: an important component in the fight against tuberculosis

W Gong, Y Liang, X Wu - BioMed Research International, 2020 - Wiley Online Library
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis, is one of
the top ten infectious diseases worldwide, and is the leading cause of morbidity from a …

Applications of bacillus Calmette–Guerin and recombinant bacillus Calmette–Guerin in vaccine development and tumor immunotherapy

Y Zheng, YW Naguib, Y Dong, Y Shi… - Expert review of …, 2015 - Taylor & Francis
Bacillus Calmette–Guerin (BCG) vaccines are attenuated live strains of Mycobacterium
bovis and are among the most widely used vaccines in the world. BCG is proven to be …

Pathogenesis of Mycobacterium bovis Infection: the Badger Model As a Paradigm for Understanding Tuberculosis in Animals

E Gormley, LAL Corner - Frontiers in Veterinary Science, 2018 - frontiersin.org
Tuberculosis in animals is caused principally by infection with Mycobacterium bovis and the
potential for transmission of infection to humans is often the fundamental driver for …

Impact of piglet oral vaccination against tuberculosis in endemic free-ranging wild boar populations

I Díez-Delgado, IA Sevilla, B Romero, E Tanner… - Preventive veterinary …, 2018 - Elsevier
Abstract The Eurasian wild boar (Sus scrofa) is the main wild reservoir of the Mycobacterium
tuberculosis complex in Mediterranean woodlands and a key risk factor for cattle …

Wild animal tuberculosis: stakeholder value systems and management of disease

E Gormley, LAL Corner - Frontiers in veterinary science, 2018 - frontiersin.org
When human health is put at risk from the transmission of animal diseases, the options for
intervention often require input from stakeholders whose differing values systems contribute …