Fibrin formation, structure and properties

JW Weisel, RI Litvinov - Fibrous proteins: structures and mechanisms, 2017 - Springer
Fibrinogen and fibrin are essential for hemostasis and are major factors in thrombosis,
wound healing, and several other biological functions and pathological conditions. The X …

Strategies to use fibrinogen as bioink for 3D bioprinting fibrin-based soft and hard tissues

BAG de Melo, YA Jodat, EM Cruz, JC Benincasa… - Acta biomaterialia, 2020 - Elsevier
Fibrin gel has been widely used for engineering various types of tissues due to its
biocompatible nature, biodegradability, and tunable mechanical and nanofibrous structural …

Fibrin mechanical properties and their structural origins

RI Litvinov, JW Weisel - Matrix Biology, 2017 - Elsevier
Fibrin is a protein polymer that is essential for hemostasis and thrombosis, wound healing,
and several other biological functions and pathological conditions that involve extracellular …

Strategies for directing the structure and function of three-dimensional collagen biomaterials across length scales

BD Walters, JP Stegemann - Acta biomaterialia, 2014 - Elsevier
Collagen type I is a widely used natural biomaterial that has found utility in a variety of
biological and medical applications. Its well-characterized structure and role as an …

Advances in on-chip vascularization

K Haase, RD Kamm - Regenerative medicine, 2017 - Taylor & Francis
Microfluidics is invaluable for studying microvasculature, development of organ-on-chip
models and engineering microtissues. Microfluidic design can cleverly control geometry …

Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation

YK Wang, CS Chen - Journal of cellular and molecular …, 2013 - Wiley Online Library
Stem cells have been shown to have the potential to provide a source of cells for
applications to tissue engineering and organ repair. The mechanisms that regulate stem cell …

Cell contact guidance via sensing anisotropy of network mechanical resistance

G Thrivikraman, A Jagiełło, VK Lai… - Proceedings of the …, 2021 - National Acad Sciences
Despite the ubiquitous importance of cell contact guidance, the signal-inducing contact
guidance of mammalian cells in an aligned fibril network has defied elucidation. This is due …

Engineering microenvironment for human cardiac tissue assembly in heart-on-a-chip platform

Y Zhao, N Rafatian, EY Wang, NT Feric, BFL Lai… - Matrix Biology, 2020 - Elsevier
Organ-on-a-chip systems have the potential to revolutionize drug screening and disease
modeling through the use of human stem cell-derived cardiomyocytes. The predictive power …

Natural polymers in heart valve tissue engineering: strategies, advances and challenges

DE Ciolacu, R Nicu, F Ciolacu - Biomedicines, 2022 - mdpi.com
In the history of biomedicine and biomedical devices, heart valve manufacturing techniques
have undergone a spectacular evolution. However, important limitations in the development …

Characterization of fibrin and collagen gels for engineering wound healing models

O Moreno-Arotzena, JG Meier, C Del Amo… - Materials, 2015 - mdpi.com
Hydrogels are used for 3D in vitro assays and tissue engineering and regeneration
purposes. For a thorough interpretation of this technology, an integral biomechanical …