Endogenous conjugation of biomimetic dinitrosyl iron complex with protein vehicles for oral delivery of nitric oxide to brain and activation of hippocampal …

CR Wu, YD Huang, YH Hong, YH Liu, M Narwane… - Jacs Au, 2021 - ACS Publications
Nitric oxide (NO), a pro-neurogenic and antineuroinflammatory gasotransmitter, features the
potential to develop a translational medicine against neuropathological conditions. Despite …

Lipophilicity of fentalogs: Comparison of experimental and computationally derived data

M Schackmuth, S Kerrigan - Journal of forensic sciences, 2023 - Wiley Online Library
Although fentanyl and a small number of derivatives used for medical or veterinary
procedures are well characterized, physiochemical properties have not been determined for …

Mechanistic and Kinetic Insights into Cellular Uptake of Biomimetic Dinitrosyl Iron Complexes and Intracellular Delivery of NO for Activation of Cytoprotective HO-1

H Chiu, A Chau Fang, YH Chen, RX Koi, KC Yu… - JACS Au, 2024 - ACS Publications
Dinitrosyl iron unit (DNIU),[Fe (NO) 2], is a natural metallocofactor for biological storage,
delivery, and metabolism of nitric oxide (NO). In the attempt to gain a biomimetic insight into …

Active sesquiterpene lactones against Leishmania amazonensis and Leishmania braziliensis

AM Sosa, S Amaya, E Salamanca Capusiri… - Natural Product …, 2016 - Taylor & Francis
Seventeen sesquiterpene lactones (SLs) isolated from five species of the tribe Vernonieae
were evaluated for their in vitro activity against promastigotes of Leishmania amazonensis …

Molecular docking and QSAR studies: noncovalent interaction between acephate analogous and the receptor site of human acetylcholinesterase

K Gholivand, AA Ebrahimi Valmoozi… - Journal of agricultural …, 2013 - ACS Publications
Twelve new compounds of acephate (Ace) analogues were synthesized and characterized
by 31P, 13C, and 1H NMR and IR spectroscopy. The probable insecticide potential of these …

The influence of plasticisers on response characteristics of anionic surfactant potentiometric sensor

M Karnaš, N Sakač, M Jozanović, M Tsakiri… - International journal of …, 2017 - Elsevier
Six different plasticisers, 2-nitrophenyl octyl ether (P1), bis (2-ethylhexyl) phthalate (P2), bis
(2-ethylhexyl) sebacate (P3), 2-nitrophenyl phenyl ether (P4), dibutyl phthalate (P5) and …

Topochemical models for the prediction of lipophilicity of 1, 3-disubstituted propan-2-one analogs

H Dureja, V Kumar, S Gupta… - Journal of Theoretical and …, 2007 - World Scientific
In the present study, the relationship between the topochemical indices and log P values of
1, 3-disubstituted propan-2-one analogs has been investigated. Three topochemical indices …

Development of antimigraine transdermal delivery systems of pizotifen malate

CE Serna-Jiménez, S del Rio-Sancho… - International Journal of …, 2015 - Elsevier
The aim of this study was to develop and evaluate a transdermal delivery system of pizotifen
malate. Pizotifen is frequently used in the preventive treatment of migraine, but is also …

Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors

S Ghadimi, S Latif Mousavi, Z Javani - Journal of Enzyme Inhibition …, 2008 - Taylor & Francis
The anti-AChE activity of phosphoramidates has been noticed for many years. Because of
the wide application of phosphoramidates in recent years, there has been a continuing …

Synthesis and biological evaluation of novel N-substituted (3-(1-aminoethylidene)-2-oxochroman-4-yl)phosphonic acid diethyl ester derivatives as anti-Alzheimer …

S Shaikh, G Pavale, MMV Ramana - Chemical Papers, 2020 - Springer
A novel scaffold of N-substituted (3-(1-aminoethylidene)-2-oxochroman-4-yl) phosphonic
acid diethyl ester derivatives was designed, synthesized and evaluated as …