The next generation of evidence-based medicine

V Subbiah - Nature medicine, 2023 - nature.com
Recently, advances in wearable technologies, data science and machine learning have
begun to transform evidence-based medicine, offering a tantalizing glimpse into a future of …

A review of the role of artificial intelligence in healthcare

A Al Kuwaiti, K Nazer, A Al-Reedy, S Al-Shehri… - Journal of personalized …, 2023 - mdpi.com
Artificial intelligence (AI) applications have transformed healthcare. This study is based on a
general literature review uncovering the role of AI in healthcare and focuses on the following …

Multimodal machine learning in precision health: A scoping review

A Kline, H Wang, Y Li, S Dennis, M Hutch, Z Xu… - npj Digital …, 2022 - nature.com
Abstract Machine learning is frequently being leveraged to tackle problems in the health
sector including utilization for clinical decision-support. Its use has historically been focused …

Artificial intelligence in drug discovery and development

KK Mak, YH Wong, MR Pichika - Drug discovery and evaluation: safety …, 2024 - Springer
This chapter comprehensively explores the pivotal role of artificial intelligence (AI) in drug
discovery and development, encapsulating its potentials, methodologies, real-world …

Artificial intelligence applied to clinical trials: opportunities and challenges

S Askin, D Burkhalter, G Calado, S El Dakrouni - Health and technology, 2023 - Springer
Abstract Background Clinical Trials (CTs) remain the foundation of safe and effective drug
development. Given the evolving data-driven and personalized medicine approach in …

Generative artificial intelligence empowers digital twins in drug discovery and clinical trials

M Bordukova, N Makarov… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction The concept of Digital Twins (DTs) translated to drug development
and clinical trials describes virtual representations of systems of various complexities …

Development of a novel dementia risk prediction model in the general population: A large, longitudinal, population-based machine-learning study

J You, YR Zhang, HF Wang, M Yang, JF Feng… - …, 2022 - thelancet.com
Background The existing dementia risk models are limited to known risk factors and
traditional statistical methods. We aimed to employ machine learning (ML) to develop a …

Treatment of pulmonary arterial hypertension: recent progress and a look to the future

M Humbert, O Sitbon, C Guignabert… - The Lancet …, 2023 - thelancet.com
Pulmonary arterial hypertension (PAH) is a severe but treatable form of pre-capillary
pulmonary hypertension caused by pulmonary vascular remodelling. As a result of basic …

The coming of age of AI/ML in drug discovery, development, clinical testing, and manufacturing: The FDA Perspectives

SK Niazi - Drug Design, Development and Therapy, 2023 - Taylor & Francis
Artificial intelligence (AI) and machine learning (ML) represent significant advancements in
computing, building on technologies that humanity has developed over millions of years …

How can machine learning and multiscale modeling benefit ocular drug development?

N Wang, Y Zhang, W Wang, Z Ye, H Chen, G Hu… - Advanced Drug Delivery …, 2023 - Elsevier
The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …