Primary hyperparathyroidism

MD Walker, SJ Silverberg - Nature Reviews Endocrinology, 2018 - nature.com
In this Review, we describe the pathogenesis, diagnosis and management of primary
hyperparathyroidism (PHPT), with a focus on recent advances in the field. PHPT is a …

Primary hyperparathyroidism

JP Bilezikian, NE Cusano, AA Khan, JM Liu… - Nature reviews Disease …, 2016 - nature.com
Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone
(PTH) is excessively secreted from one or more of the four parathyroid glands. A single …

The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases

JR Finnerty, WX Wang, SS Hébert, BR Wilfred… - Journal of molecular …, 2010 - Elsevier
The miR-15/107 group of microRNA (miRNA) gene is increasingly appreciated to serve key
functions in humans. These miRNAs regulate gene expression involved in cell division …

The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2

CCL Wong, CM Wong, EKK Tung, SLK Au, JMF Lee… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: We investigated mechanisms of hepatocellular carcinoma (HCC)
metastasis and identified an antimetastatic microRNA (miRNA), miR-139, that is down …

MiR‐503 regulates osteoclastogenesis via targeting RANK

C Chen, P Cheng, H Xie, HD Zhou… - Journal of Bone and …, 2014 - academic.oup.com
MicroRNAs (miRNAs) play important roles in osteoclastogenesis and bone resorption.
However, no study has investigated the role of miRNA in postmenopausal osteoporosis …

Human microRNA hsa-miR-296-5p suppresses enterovirus 71 replication by targeting the viral genome

Z Zheng, X Ke, M Wang, S He, Q Li, C Zheng… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) has emerged as a major cause of neurological disease
following the near eradication of poliovirus. Accumulating evidence suggests that …

The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma

DM Özata, S Caramuta… - Endocrine-related …, 2011 - erc.bioscientifica.com
Adrenocortical carcinoma (ACC) is an aggressive tumor showing frequent metastatic spread
and poor survival. Although recent genome-wide studies of ACC have contributed to our …

The role of microRNAs in osteoclasts and osteoporosis

P Tang, Q Xiong, W Ge, L Zhang - RNA biology, 2014 - Taylor & Francis
Osteoclasts are the exclusive cells of bone resorption. Abnormally activating osteoclasts can
lead to low bone mineral density, which will cause osteopenia, osteoporosis, and other bone …

Molecular and clinical spectrum of primary hyperparathyroidism

S Jha, WF Simonds - Endocrine Reviews, 2023 - academic.oup.com
Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

miR-139-5p inhibits aerobic glycolysis, cell proliferation, migration, and invasion in hepatocellular carcinoma via a reciprocal regulatory interaction with ETS1

S Hua, L Lei, L Deng, X Weng, C Liu, X Qi, S Wang… - Oncogene, 2018 - nature.com
Cancer cells have metabolic features that allow them to preferentially metabolize glucose
through aerobic glycolysis, providing them with a progression advantage. However …