Cellular mitophagy means that cells selectively wrap and degrade damaged mitochondria
through an autophagy mechanism, thus maintaining mitochondria and intracellular …

Mitochondrial function is maintained by several strictly coordinated mechanisms, collectively
termed mitochondrial quality control mechanisms, including fusion and fission, degradation …

The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …

Injury to the renal tubular epithelium has emerged as a leading factor underlying the
formation of kidney stones. Indeed, epithelial cell damage contributes to the adherence and …

Diabetic kidney disease (DKD) is a major diabetic complication and global health concern,
occurring in nearly 30% to 40% of people with diabetes. Importantly, several therapeutic …

The kidney contains numerous mitochondria in proximal tubular cells that provide energy for
tubular secretion and reabsorption. Mitochondrial injury and consequent excessive reactive …

Neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease,
significantly reduce the quality of life of patients and eventually result in complete …

The patients with kidney diseases are increasing rapidly all over the world. With the rich
abundance of mitochondria, kidney is an organ with a high consumption of energy. Hence …

Mitophagy maintains cellular homeostasis by eliminating damaged mitochondria.
Accumulated damaged mitochondria can lead to oxidative stress and cell death. Induction of …

Mitochondrial autophagy (mitophagy) is very important process for the maintenance of
cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk …