Interferon (IFN)-γ is the uppermost cytokine implicated in anti-tumor immunity. With its
cytostatic, pro-apoptotic and immune-provoking effects, IFN-γ plays a central role in the …

Interferon regulatory factors (IRFs) are a group of closely related proteins collectively
referred to as the IRF family. Members of this family were originally recognized for their roles …

Abstract Interferon regulatory factor 1 (IRF1) regulates diverse biological functions, including
modulation of cellular responses involved in tumorigenesis. Genetic mutations and altered …

Resistance to antitumor treatment contributes to patient mortality. Functional proteomic
screening of organoids derived from chemotherapy-treated patients with breast cancer …

Interferon-gamma (IFN-γ) is a pleiotropic cytokine with immunomodulatory, anti-viral, and
anti-proliferative effects. In this study, we examined the effects of IFN-γ on autophagy and …

Abstract Interferon regulatory factor 1 (IRF-1) is a tumor suppressor gene in cancer biology
with anti-proliferative and pro-apoptotic effect on cancer cells, however mechanisms of IRF-1 …

The quantity of mRNA transcripts in a cell is determined by a complex interplay of
cooperative and counteracting biological processes. Independent Component Analysis …

Interferon regulatory factor 1 (IRF1), a critical member of the IRF family, was previously
shown to be associated with the immune system and to be involved in apoptosis and tumor …

The B-aggressive lymphoma-1 protein and ADP-ribosyltransferase BAL1/ARTD9 has been
recently identified as a risk-related gene product in aggressive diffuse large B-cell …

Background CHK1 is considered an oncogene with overexpression in numerous cancers.
However, CHK1 signalling regulation in hepatocellular carcinoma (HCC) remains unclear …