Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures

T Pandics, D Major, V Fazekas-Pongor, Z Szarvas… - Geroscience, 2023 - Springer
The aging population worldwide is facing a significant increase in age-related non-
communicable diseases, including cardiovascular and brain pathologies. This …

Mass spectrometry analysis of DNA and protein adducts as biomarkers in human exposure to cigarette smoking: acrolein as an example

HJC Chen - Chemical Research in Toxicology, 2023 - ACS Publications
Acrolein is a major component in cigarette smoke and a product of endogenous lipid
peroxidation. It is difficult to distinguish human exposure to acrolein from exogenous sources …

Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress-related PERK pathway in MIN6 cells

X Zhang, L Jiang, H Chen, S Wei, K Yao, X Sun… - Toxicology, 2022 - Elsevier
Acrolein is a typical food and environmental pollutant and a risk factor for diabetes. The
primary pathogenesis of diabetes is insulin deficiency and resistance. Ferroptosis is an iron …

The emission of VOCs and CO from heated tobacco products, electronic cigarettes, and conventional cigarettes, and their health risk

F Lu, M Yu, C Chen, L Liu, P Zhao, B Shen, R Sun - Toxics, 2021 - mdpi.com
The differences in aerosol composition between new tobacco types (heated tobacco
products and electronic cigarettes) and conventional cigarettes have not been systematically …

Increased serum levels of aldehydes are associated with cardiovascular disease and cardiovascular risk factors in adults

C Xu, J Liang, S Xu, Q Liu, J Xu, A Gu - Journal of Hazardous Materials, 2020 - Elsevier
Previous studies have identified several genetic and environmental risk factors for
cardiovascular disease (CVD), but little is known about the associations between serum …

Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature

Y Jiang, X Li, Y Zhang, B Wu, Y Li… - … Reviews in Food …, 2024 - Wiley Online Library
Foodborne contaminants refer to substances that are present in food and threaten food
safety. Due to the progress in detection technology and the rising concerns regarding public …

Quercetin alleviates atherosclerosis by suppressing oxidized LDL-induced senescence in plaque macrophage via inhibiting the p38MAPK/p16 pathway

G Luo, L Xiang, L Xiao - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Quercetin is a widely known and biologically active phytochemical and exerts therapeutic
effects against atherosclerosis. The removal of senescent plaque macrophages effectively …

Catechins in green tea powder (matcha) are heat-stable scavengers of acrolein, a lipid peroxide-derived reactive carbonyl species

K Sugimoto, Y Matsuoka, K Sakai, N Fujiya, H Fujii… - Food Chemistry, 2021 - Elsevier
Lipid peroxidation-derived reactive carbonyl species (RCS) such as acrolein and 4-
hydroxynonenal pose health risks. We characterized the RCS-scavenging reactions of tea …

Interaction of acrylamide, acrolein, and 5-hydroxymethylfurfural with amino acids and DNA

J Ou, J Zheng, J Huang, CT Ho… - Journal of agricultural and …, 2020 - ACS Publications
Acrylamide, acrolein, and 5-hydroxymethylfurfural (HMF) are food-borne toxicants produced
during the thermal processing of food. The α, β-unsaturated carbonyl group or aldehyde …

Urinary volatile organic compound metabolites and reduced lung function in US adults

A Mendy, S Burcham, AL Merianos, TB Mersha… - Respiratory …, 2022 - Elsevier
Abstract Background Volatile organic compounds (VOCs) are associated with adverse
respiratory outcomes at high occupational exposures. However, whether exposure levels …