Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …

Mammalian cell invasion by the protozoan pathogen Trypanosoma cruzi is critical to its
survival in the host. To promote its entry into a wide variety of non‐professional phagocytic …

Trypanosoma cruzi, the agent of Chagas disease, probably infects tens of millions of people,
primarily in Latin America, causing morbidity and mortality. The options for treatment and …

To complement the sequencing of the three kinetoplastid genomes reported in this issue, we
have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of …

Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite,
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …

Background Chronic chagasic cardiomyopathy is a debilitating and frequently fatal outcome
of human infection with the protozoan parasite, Trypanosoma cruzi. Microarray analysis of …

Trypomastigotes, the highly motile infective forms of Trypanosoma cruzi, are capable of
infecting several cell types. Invasion occurs either by direct recruitment and fusion of …

The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an
obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful …

Trypanosoma cruzi actively invades mammalian cells by forming parasitophorous vacuoles
(PVs). After entry, the parasite has to escape from these vacuoles in order to replicate inside …

The trypanosomatid (protozoan) parasites Trypanosoma cruzi and Leishmania spp. are
causative agents of Chagas disease and Leishmaniasis, respectively. They display high …