Arctigenin: pharmacology, total synthesis, and progress in structure modification

D Wu, L Jin, X Huang, H Deng, Q Shen… - Journal of Enzyme …, 2022 - Taylor & Francis
Arctium lappa L. is a prevalent medicinal herb and a health supplement that is commonly
used in Asia. Over the last few decades, the bioactive component arctigenin has attracted …

Management of triple-negative breast cancer by natural compounds through different mechanistic pathways

M Kaleem, M Thool, NG Dumore… - Frontiers in …, 2024 - frontiersin.org
Triple-negative breast cancer (TNBC) is the most severe form of breast cancer,
characterized by the loss of estrogen, progesterone, and human epidermal growth factor …

[HTML][HTML] Isolation of oleanolic acid from Lavandula stoechas and its potent anticancer properties against MCF-7 cancer cells via induced apoptosis

HM Rasheed, U Farooq, K Bashir, F Wahid… - Journal of King Saud …, 2023 - Elsevier
Medicinal plants are natural resources of diversified therapeutic metabolites. Lavandula
stoechas has been used traditionally for the management of different metabolic disorders …

[HTML][HTML] Anti-inflammatory effects of TNF-α and ASK1 inhibitory compounds isolated from Schkuhria pinnata used for the treatment of dermatitis

LA Ticona, BH Povo, JS Sánchez-Corral… - Journal of …, 2024 - Elsevier
Abstract Ethno-pharmacological relevance The Andean Schkuhria pinnata species
commonly known as 'Canchalagua'is used as an infusion in Andean countries to treat …

Folecitin Isolated from Hypericum oblongifolium Exerts Neuroprotection against Lipopolysaccharide‐Induced Neuronal Synapse and Memory Dysfunction via p‐AKT …

U Farooq, MUK Sahibzada, T Khan… - Evidence‐Based …, 2022 - Wiley Online Library
Neurodegenerative diseases, especially Alzheimer's disease (AD), are characterised with
neuronal synapse and memory dysfunction, and thus, there is an urgent need to find novel …

Phytochemical Profiling, Antioxidant Activity, and In Silico Analyses of Sterculia villosa and Vernonia patula

C Lyzu, S Mitra, K Perveen, Z Khan… - Evidence‐Based …, 2022 - Wiley Online Library
Our study aims to evaluate the chemical profiles and antioxidant activities of a methanolic
extract of Sterculia villosa bark (MESV) and a methanolic extract of the Vernonia patula …

GC–MS based antioxidants characterization in Saussurea heteromalla (D. Don) Hand-Mazz by inhibition of nitric oxide generation in macrophages

Saboon, A Iqbal, Y Bibi, T Afzal, A Sher, A Qayyum… - Scientific Reports, 2024 - nature.com
For centuries, medicinal plants have served as the cornerstone for traditional health care
systems and same practice is still prevalent today. In the Himalayan region, Saussurea …

Cytotoxicity and molecular-docking approach of a new rosane-type diterpenoid from the roots of Euphorbia nematocypha

N Song, X Zheng, J Wang, L Zhu, C Wang, L Cai… - Frontiers in …, 2022 - frontiersin.org
A new rosane-type diterpenoid (1) along with nine known diterpenoids (2–10), were isolated
from the dried roots of Euphorbia nematocypha. The absolute configuration was elucidated …

Antioxidant-Activity-Guided Purification and Separation of Octocrylene from Saussurea heteromalla

Saboon, Y Bibi, SA Ayoubi, T Afzal, S Gilani, K Malik… - Separations, 2023 - mdpi.com
Plants have been a source of medicine since ancient times, and such traditional medications
are widely practiced nowadays. Saussurea heteromalla is widely used in traditional …

Acute toxicity appraisal of Saussurea heteromalla extract and development of its chemotherapeutic herbal dosage form

A Batool, M Muddassir, BH Alshammari, TG Alsahli… - Plos one, 2024 - journals.plos.org
Ethnopharmacological relevance of Saussurea species for anti-cancer compounds
instigated us to develop chemotherapeutic herbal tablets. This study was an ongoing part of …