Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …

Diseases intrinsic to the pancreas such as pancreatitis, pancreatic cancer and type 1
diabetes mellitus impart substantial health and financial burdens on society but identification …

The clinical management of cancer has evolved in recent years towards more personalized
strategies that require a comprehensive knowledge of the complex molecular features …

There remains tremendous interest in developing liquid biopsy assays for detection of
cancer‐specific alterations, such as mutations and DNA methylation, in cell‐free DNA …

Screening for early‐stage disease is vital for reducing colorectal cancer (CRC)‐related
mortality. Methylation of circulating tumor DNA has been previously used for various types of …

Background & Aims It is a challenge to accurately assess pancreatic cystic lesions (PCLs)
and determine their risk. We compared the yield of tissue acquired with endoscopic …

Abstract Background Objectives: Pancreatic cysts are frequently detected in high-risk
individuals (HRI) undergoing surveillance for pancreatic cancer. The International Cancer of …

In the previous decade, comprehensive genomic analyses have yielded important insights
about the genetic alterations that underlie pancreatic tumorigenesis. Whole-exome and …

Background Patients with pancreatobiliary tract cancer usually have a poor clinical outcome,
with a 5-year overall survival rate below 20%. This is mainly associated with the late …

Pancreatic cystic lesions are increasingly detected in cross-sectional imaging. Intraductal
papillary mucinous neoplasm (IPMN) is a mucin-producing subtype of the pancreatic cyst …