Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in
central nervous system (CNS) drug delivery, since they block most molecules from entering …

Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly
interesting biomaterialover the past few years. It constitutes a novel perspective in drug …

A series of studies have reported on the salubrious effects of oxytocin nasal spray on social
cognition and behavior in humans, across physiology (eg, eye gaze, heart rate variability) …

The nose-to-brain pathway has been proven to be a shortcut for direct drug delivery to the
brain. However, whether and to what extent nanoparticles can be delivered through this …

Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …

As a non-invasive route, intranasal administration offers patient comfort and compliance
which are hurdled in parenteral drug therapy. In addition, the current recognition that the …

Accumulating evidence demonstrates the important role of oxytocin (OT) in the modulation of
social cognition and behavior. This has led many to suggest that the intranasal …

Drug delivery to the brain represents a challenge, especially in the therapy of central
nervous system malignancies. Simvastatin (SVT), as with other statins, has shown potential …

Context: In recent years, nanotechnology-based delivery systems have gained interest to
overcome the problems of restricted absorption of therapeutic agents from the nasal cavity …