A network-biology perspective of microRNA function and dysfunction in cancer

CP Bracken, HS Scott, GJ Goodall - Nature Reviews Genetics, 2016 - nature.com
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …

The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

Epigenetics and cervical cancer: from pathogenesis to therapy

J Fang, H Zhang, S Jin - Tumor Biology, 2014 - Springer
Although human papillomavirus (HPV) infection has been found in most of the cervical
cancer cases, additional genetic and epigenetic changes are required for disease …

Long non-coding RNA HOTAIR inhibits miR-17-5p to regulate osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head

B Wei, W Wei, B Zhao, X Guo, S Liu - PloS one, 2017 - journals.plos.org
Background and aim The biological functions of non-coding RNAs (ncRNAs) have been
widely identified in many human diseases. In the present study, the relationship between …

Long noncoding RNA H19 competitively binds miR‐17‐5p to regulate YES 1 expression in thyroid cancer

L Liu, J Yang, X Zhu, D Li, Z Lv, X Zhang - The FEBS journal, 2016 - Wiley Online Library
The long noncoding RNA H19 is overexpressed in many cancers and acts as an oncogene.
Here, we investigated the role of H19 in thyroid carcinogenesis and its relation to micro RNA …

[HTML][HTML] Micromanaging aerobic respiration and glycolysis in cancer cells

AV Orang, J Petersen, RA McKinnon, MZ Michael - Molecular metabolism, 2019 - Elsevier
Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic
pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic …

Cervical cancer and HPV infection: ongoing therapeutic research to counteract the action of E6 and E7 oncoproteins

AM Almeida, JA Queiroz, F Sousa, Â Sousa - Drug discovery today, 2019 - Elsevier
Highlights•Human papillomavirus (HPV) has a primordial role in the development of cervical
cancer.•Therapies currently available for cervical cancer treatment are reviewed.•The …

MicroRNA in cervical cancer: OncomiRs and tumor suppressor miRs in diagnosis and treatment

K Banno, M Iida, M Yanokura, I Kisu… - The Scientific World …, 2014 - Wiley Online Library
Cervical cancer is a female‐specific disease with a high incidence and mortality. MicroRNAs
(miRNAs) are implicated in posttranscriptional regulation of gene expression and in the …

miR-139-5p is a regulator of metastatic pathways in breast cancer

K Krishnan, AL Steptoe, HC Martin, DR Pattabiraman… - Rna, 2013 - rnajournal.cshlp.org
Metastasis is a complex, multistep process involved in the progression of cancer from a
localized primary tissue to distant sites, often characteristic of the more aggressive forms of …