The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …

The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

VSELs express some ESC markers, such as stage-specific antigen (SSEA), nuclear Oct-4A
(octamer-binding transcription factor 4A), Nanog, and Rex1. The true expression of these …

The core functions of stem cells (SCs) are critically regulated by their cellular redox status.
Glutathione is the most abundant non-protein thiol functioning as an antioxidant and a redox …

Chemotherapy is the standard care for patients with gastric cancer (GC); however,
resistance to existing drugs has limited its success. The persistence of cancer stem cells …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, which is
associated with memory deficit and global cognitive decline. Age is the greatest risk factor …

Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious
attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related …

Methionine metabolism is critical for epigenetic maintenance, redox homeostasis, and
animal development. However, the regulation of methionine metabolism remains unclear …

Aberrant activation of embryogenesis-related molecular programs in urothelial bladder
cancer (BC) is associated with stemness features related to oncogenic dedifferentiation and …