Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research

LM Swift, MW Kay, CM Ripplinger… - American Journal of …, 2021 - journals.physiology.org
Optical mapping is an imaging technique that is extensively used in cardiovascular
research, wherein parameter-sensitive fluorescent indicators are used to study the …

A technical review of optical mapping of intracellular calcium within myocardial tissue

R Jaimes III, RD Walton, P Pasdois… - American Journal …, 2016 - journals.physiology.org
Optical mapping of Ca2+-sensitive fluorescence probes has become an extremely useful
approach and adopted by many cardiovascular research laboratories to study a spectrum of …

β-Adrenergic stimulation and rapid pacing mutually promote heterogeneous electrical failure and ventricular fibrillation in the globally ischemic heart

V Garg, T Taylor, M Warren… - American Journal …, 2015 - journals.physiology.org
Global ischemia, catecholamine surge, and rapid heart rhythm (RHR) due to ventricular
tachycardia or ventricular fibrillation (VF) are the three major factors of sudden cardiac arrest …

Cyclosporine-insensitive mode of cell death after prolonged myocardial ischemia: Evidence for sarcolemmal permeabilization as the pivotal step

KJ Sciuto, SW Deng, PW Venable, M Warren… - Plos one, 2018 - journals.plos.org
A prominent theory of cell death in myocardial ischemia/reperfusion (I/R) posits that the
primary and pivotal step of irreversible cell injury is the opening of the mitochondrial …

Optical mapping of cardiac electromechanics

MW Kay, IR Efimov - Biophysical Journal, 2016 - cell.com
Cardiac biophysics rests on three fundamental pillars: energy production, electrical
excitation, and mechanical work. Studies of cardiac metabolism, bioelectricity, and …

[PDF][PDF] Microstructural analysis of endomyocardial biopsies

X Buyse Sanchez - 2018 - upcommons.upc.edu
Abstract According to the World Health Organization, cardiovascular diseases are the cause
of the 31% of deaths in the world. A better understanding of the cardiac microstructure and …