COVID‐19: Thrombosis, thromboinflammation, and anticoagulation considerations

JH Levy, T Iba, LB Olson, KM Corey… - … journal of laboratory …, 2021 - Wiley Online Library
Vascular endothelial injury is a hallmark of acute infection at both the microvascular and
macrovascular levels. The hallmark of SARS‐CoV‐2 infection is the current COVID‐19 …

Hemostatic challenges in neonates

P Davenport, M Sola-Visner - Frontiers in pediatrics, 2021 - frontiersin.org
The neonatal hemostatic system is strikingly different from that of adults. Among other
differences, neonates exhibit hyporeactive platelets and decreased levels of coagulation …

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6–17 years: a preliminary report of COV006, a phase 2 single-blind …

G Li, F Cappuccini, NG Marchevsky, PK Aley, R Aley… - The Lancet, 2022 - thelancet.com
Background Vaccination of children and young people against SARS-CoV-2 is
recommended in some countries. Scarce data have been published on immune responses …

Use of antifibrinolytics in pediatric life-threatening hemorrhage: a prospective observational multicenter study

PC Spinella, JC Leonard, BA Gaines… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: To assess the impact of antifibrinolytics in children with life-threatening
hemorrhage. DESIGN: Secondary analysis of the MAssive Transfusion epidemiology and …

Anticoagulation-free pediatric extracorporeal membrane oxygenation: Single-center retrospective study

EJ Rabinowitz, MT Danzo, MJ Anderson… - Pediatric Critical Care …, 2023 - journals.lww.com
Objectives: To analyze hemorrhage and thrombosis data related to anticoagulation-free
pediatric extracorporeal membrane oxygenation (ECMO). Design: Retrospective cohort …

High-throughput microfluidic blood testing to phenotype genetically linked platelet disorders: an aid to diagnosis

DI Fernandez, I Provenzale, M Canault, S Fels… - Blood …, 2023 - ashpublications.org
Linking the genetic background of patients with bleeding diathesis and altered platelet
function remains challenging. We aimed to assess how a multiparameter microspot-based …

Frailty score and outcomes of patients undergoing vascular surgery and amputation: A systematic review and meta-analysis

S Chen, R Dunn, M Jackson, N Morley… - Frontiers in …, 2023 - frontiersin.org
Introduction Frailty is associated with adverse postoperative health outcomes, including
increased mortality, longer length of stay, higher rehospitalization, and other complications …

Predictors of venous thromboembolism among infants in children's hospitals in the United States: a retrospective Pediatric Health Information Study

MC Easterlin, Y Li, L Yieh, CL Gong, J Jaffray… - Journal of …, 2022 - nature.com
Abstract Objectives Examine:(1) Prevalence of diagnosed venous thromboembolism (VTE)
in infants< 6 months discharged from US NICUs;(2) Associations between …

Comparison of standard and global hemostasis assays in cord and peripheral blood of newborns

BV Arutunyan, EM Koltsova, MA Shpilyuk… - Pediatric …, 2024 - nature.com
Background Umbilical cord blood is used for the testing of various parameters in newborns.
However, data on its applicability for hemostasis assays is insufficient. Objective To evaluate …

Neonatal coagulopathies: A review of established and emerging treatments

N Moiseiwitsch, AC Brown - Experimental Biology and …, 2021 - journals.sagepub.com
Despite the relative frequency of both bleeding and clotting disorders among patients
treated in the neonatal intensive care unit, few clear guidelines exist for treatment of …