In silico mathematical modelling for glioblastoma: a critical review and a patient-specific case

J Falco, A Agosti, IG Vetrano, A Bizzi, F Restelli… - Journal of clinical …, 2021 - mdpi.com
Glioblastoma extensively infiltrates the brain; despite surgery and aggressive therapies, the
prognosis is poor. A multidisciplinary approach combining mathematical, clinical and …

[HTML][HTML] On the long time behavior of a tumor growth model

A Miranville, E Rocca, G Schimperna - Journal of Differential Equations, 2019 - Elsevier
We consider the problem of the long time dynamics for a diffuse interface model for tumor
growth. The model describes the growth of a tumor surrounded by host tissues in the …

On a Cahn–Hilliard–Keller–Segel model with generalized logistic source describing tumor growth

E Rocca, G Schimperna, A Signori - Journal of Differential Equations, 2023 - Elsevier
We propose a new type of diffuse interface model describing the evolution of a tumor mass
under the effects of a chemical substance (eg, a nutrient or a drug). The process is described …

A computational framework for the personalized clinical treatment of glioblastoma multiforme

A Agosti, C Cattaneo, C Giverso… - ZAMM‐Journal of …, 2018 - Wiley Online Library
In this work, we develop a computational tool to predict the patient‐specific evolution of a
highly malignant brain tumour, the glioblastoma multiforme (GBM), and its response to …

Long-time dynamics and optimal control of a diffuse interface model for tumor growth

C Cavaterra, E Rocca, H Wu - Applied Mathematics & Optimization, 2021 - Springer
We investigate the long-time dynamics and optimal control problem of a thermodynamically
consistent diffuse interface model that describes the growth of a tumor in presence of a …

On a phase field model of Cahn–Hilliard type for tumour growth with mechanical effects

H Garcke, KF Lam, A Signori - Nonlinear Analysis: Real World Applications, 2021 - Elsevier
Mechanical effects have mostly been neglected so far in phase field tumour models that are
based on a Cahn–Hilliard approach. In this paper we study a macroscopic mechanical …

Pattern formation features might explain homoplasy: fertile surfaces in higher fungi as an example

F Kuhar, L Terzzoli, E Nouhra, G Robledo… - Theory in Biosciences, 2022 - Springer
Fungi show a high degree of morphological convergence. Regarded for a long time as an
obstacle for phylogenetic studies, homoplasy has also been proposed as a source of …

Cahn-Hilliard-Brinkman systems for tumour growth

M Ebenbeck, H Garcke, R Nürnberg - arXiv preprint arXiv:2003.08314, 2020 - arxiv.org
A phase field model for tumour growth is introduced that is based on a Brinkman law for
convective velocity fields. The model couples a convective Cahn-Hilliard equation for the …

Degenerate Cahn-Hilliard and incompressible limit of a Keller-Segel model

C Elbar, B Perthame, A Poulain - arXiv preprint arXiv:2112.10394, 2021 - arxiv.org
The Keller-Segel model is a well-known system representing chemotaxis in living
organisms. We study the convergence of a generalized nonlinear variant of the Keller-Segel …

On a Cahn--Hilliard--Brinkman Model for Tumor Growth and Its Singular Limits

M Ebenbeck, H Garcke - SIAM Journal on Mathematical Analysis, 2019 - SIAM
In this work, we study a model consisting of a Cahn--Hilliard-type equation for the
concentration of tumor cells coupled to a reaction-diffusion-type equation for the nutrient …