Deintensification of treatment for human papillomavirus-related oropharyngeal cancer: Current state and future directions

EO Bigelow, TY Seiwert, C Fakhry - Oral oncology, 2020 - Elsevier
Human papillomavirus (HPV)-related oropharyngeal squamous cell cancer (OPSCC) has
emerged as a distinct clinical entity of head and neck cancer with expected high survival …

Prognostic significance of extranodal extension in HPV-mediated oropharyngeal carcinoma: a systematic review and meta-analysis

L Benchetrit, SJ Torabi, B Givi… - … –Head and Neck …, 2021 - journals.sagepub.com
Objective To determine the prognostic role of extranodal extension (ENE) among patients
with human papilloma virus–positive (HPV+) oropharyngeal squamous cell carcinoma …

Prognostic importance of radiologic extranodal extension in HPV-positive oropharyngeal carcinoma and its potential role in refining TNM-8 cN-classification

SH Huang, B O'Sullivan, J Su, E Bartlett, J Kim… - Radiotherapy and …, 2020 - Elsevier
Purpose This study examines outcome heterogeneity and potential to refine the TNM-8 cN-
classification using radiologic extranodal extension (rENE) in a contemporary HPV-positive …

Oropharyngeal squamous cell carcinoma in 390 patients: analysis of clinical and histological criteria which significantly impact outcome

LDR Thompson, R Burchette, S Iganej… - Head and Neck …, 2020 - Springer
This study evaluates the prognostic impact of several factors in oropharyngeal squamous
cell carcinoma (OPSCC), controlling for human papillomavirus (HPV)-associated tumors and …

Response: FIGO staging of endometrial cancer 2023

N Concin, X Matias-Guiu… - … and obstetrics: the …, 2024 - pubmed.ncbi.nlm.nih.gov
Response: FIGO staging of endometrial cancer 2023 Response: FIGO staging of endometrial
cancer 2023 Int J Gynaecol Obstet. 2024 Jan;164(1):369-372. doi: 10.1002/ijgo.15277. Epub …

Significance of extranodal extension in surgically treated HPV-positive oropharyngeal carcinomas

A Beltz, S Zimmer, I Michaelides, K Evert… - Frontiers in …, 2020 - frontiersin.org
Squamous cell carcinomas of the head and neck are the subject of numerous current
studies, especially in view of the increasing incidence of tumors induced by human …

IsoMAG—An Automated System for the Immunomagnetic Isolation of Squamous Cell Carcinoma-Derived Circulating Tumor Cells

A Gribko, J Stiefel, L Liebetanz, SM Nagel, J Künzel… - Diagnostics, 2021 - mdpi.com
Background: detailed information about circulating tumor cells (CTCs) as an indicator of
therapy response and cancer metastasis is crucial not only for basic research but also for …

Impact of Multiprofessional Radiotherapy Peer Review on Multidisciplinary Team Meeting Staging in Head and Neck Cancer

K Chiu, A Gupta, T Afxentiou, A Ashraf, R Kanani… - Clinical Oncology, 2024 - Elsevier
Aims Cancer staging is routinely done in a multidisciplinary team meeting (MDM). There is
however no established quality assurance (QA) for MDM-recorded cancer staging …

Identification of cytokeratin24 as a tumor suppressor for the management of head and neck cancer

D Gül, N Habtemichael, D Dietrich, J Dietrich… - Biological …, 2022 - degruyter.com
To improve management of head and neck squamous cell carcinoma patients, we need to
increase our understanding of carcinogenesis, to identify biomarkers, and drug targets. This …

Diagnostic challenges and prognostic implications of extranodal extension in head and neck cancer: a state of the art review and gap analysis

CE Henson, AK Abou-Foul, DJ Morton… - Frontiers in …, 2023 - frontiersin.org
Extranodal extension (ENE) is a pattern of cancer growth from within the lymph node (LN)
outward into perinodal tissues, critically defined by disruption and penetration of the tumor …