Background In preterm newborns, the ductus arteriosus frequently fails to close and the
infants require medical or surgical closure of the patent ductus arteriosus (PDA). A PDA can …

Background Indomethacin is used as standard therapy to close a patent ductus arteriosus
(PDA) but is associated with reduced blood flow to several organs. Ibuprofen, another cyclo …

Objective To compare early routine pharmacologic treatment of moderate-to-large patent
ductus arteriosus (PDA) at the end of week 1 with a conservative approach that requires …

The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in
neonates. While there have been several studies and thousands of publications on the topic …

Preterm infants are at increased risk for patent ductus arteriosus (PDA). Prolonged exposure
to PDA may be deleterious and has been associated with neonatal morbidity and mortality …

Background: The identification of independent clinical risk factors for necrotizing
enterocolitis (NEC) may contribute to early selection of infants at risk, allowing for the …

Our aim was to assess the efficacy and safety of intravenous (iv) paracetamol vs. iv
ibuprofen for the treatment of hemodynamically significant patent ductus arteriosus (hsPDA) …

Background: Patent ductus arteriosus (PDA) is the persistence of a fetal shunt between the
pulmonary artery and the aorta. This structure normally closes in the first 3 days after birth; …

Objective To evaluate the effectiveness of drugs used to constrict patent ductus arteriosus
(PDA) in newborns< 28 weeks. Methods We performed a secondary analysis of the multi …

In preterm infants, failure or delay in spontaneous closure of Ductus Arteriosus (DA),
resulting in the condition of Patent Ductus Arteriosus (PDA), represents a significant issue. A …