Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics

GS Chaudhry, A Md Akim, YY Sung… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …

Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

A review of medicinal plants of the himalayas with anti-proliferative activity for the treatment of various cancers

H Regassa, A Sourirajan, V Kumar, S Pandey… - Cancers, 2022 - mdpi.com
Simple Summary Drugs are used to treat cancer. Most drugs available in the market are
chemosynthetic drugs and have side effects on the patient during and after the treatment, in …

The most competent plant-derived natural products for targeting apoptosis in cancer therapy

S Rajabi, M Maresca, AV Yumashev, R Choopani… - Biomolecules, 2021 - mdpi.com
Cancer is a challenging problem for the global health community, and its increasing burden
necessitates seeking novel and alternative therapies. Most cancers share six basic …

Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature

FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …

Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases:“reverse pharmacology” and “bedside to bench” approach

B B. Aggarwal, S Prasad, S Reuter… - Current drug …, 2011 - benthamdirect.com
Inflammation, although first characterized by Cornelius Celsus, a physician in first Century
Rome, it was Rudolf Virchow, a German physician in nineteenth century who suggested a …

The genus Inula and their metabolites: From ethnopharmacological to medicinal uses

AML Seca, A Grigore, DCGA Pinto… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance The genus Inula comprises more than one
hundred species widespread in temperate regions of Europe and Asia. Uses of this genus …

Natural products: promising resources for cancer drug discovery

S Mondal, S Bandyopadhyay… - Anti-Cancer Agents …, 2012 - benthamdirect.com
Natural products are important sources of anti-cancer lead molecules. Many successful anti-
cancer drugs are natural products or their analogues. Many more are under clinical trials …

Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction

M Khan, F Yi, A Rasul, T Li, N Wang, H Gao, R Gao… - IUBMB …, 2012 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most malignant and aggressive primary brain tumor in
adults. Despite concerted efforts to improve current therapies, the prognosis of glioblastoma …

Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone

A Rasul, M Khan, M Ali, J Li, X Li - The Scientific World Journal, 2013 - Wiley Online Library
Alantolactone and isoalantolactone, main bioactive compounds that are present in many
medicinal plants such as Inula helenium, L. Inula japonica, Aucklandia lappa, Inula …