[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Exploring faba beans (Vicia faba L.): bioactive compounds, cardiovascular health, and processing insights

Z Feng, JD Morton, E Maes, L Kumar… - Critical Reviews in …, 2024 - Taylor & Francis
Faba beans (Vicia faba L.), integral to the legume family, are a significant component of the
global pulse market because of their nutritional richness and positive health implications …

Metagenomic-Metabolomic Mining of Kinema, a Naturally Fermented Soybean Food of the Eastern Himalayas

P Kharnaior, JP Tamang - Frontiers in Microbiology, 2022 - frontiersin.org
Kinema is a popular sticky fermented soybean food of the Eastern Himalayan regions of
North East India, east Nepal, and south Bhutan. We hypothesized that some dominant …

Targeting cell signaling pathways in lung cancer by bioactive phytocompounds

N Choudhary, S Bawari, JT Burcher, D Sinha, D Tewari… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …

Bridging the gaps between plant and human health: A systematic review of soyasaponins

PS Yates, J Roberson, LK Ramsue… - Journal of Agricultural …, 2021 - ACS Publications
Saponins, prominent secondary plant metabolites, are recognized for their roles in plant
defense and medicinal benefits. Soyasaponins, commonly derived from legumes, are a …

Echinacoside inhibits the proliferation, migration, invasion and angiogenesis of ovarian cancer cells through PI3K/AKT pathway

J Liu, N Tang, N Liu, P Lei, F Wang - Journal of molecular histology, 2022 - Springer
Echinacoside is a group of natural compounds extracted from medicinal plants Cistanche
and Echinacea, which has neuroprotective, antiaging, immunomodulatory and anticancer …

Gastrointestinal biotransformation of phytochemicals: Towards futuristic dietary therapeutics and functional foods

B Singh, G Mal, D Sharma, R Sharma… - Trends in Food Science …, 2020 - Elsevier
Background Gastrointestinal (GI) microbiome is a highly diverse and intricate symbiotic
ecosystem that offers a multitude of metabolic and adaptive benefits to the host. Diverse …

Metabolomics as a tool to study underused soy parts: In search of bioactive compounds

FS Bragagnolo, CS Funari, E Ibáñez, A Cifuentes - Foods, 2021 - mdpi.com
The valorization of agri-food by-products is essential from both economic and sustainability
perspectives. The large quantity of such materials causes problems for the environment; …

Comprehensive review on signaling pathways of dietary saponins in cancer cells suppression

Y Zhou, AA Farooqi, B Xu - Critical Reviews in Food Science and …, 2023 - Taylor & Francis
Nutrigenomics utilizes high-throughput genomic technologies to reveal changes in gene
and protein levels. Excitingly, ever-growing body of scientific findings has provided sufficient …

Identification and Characterization of MortaparibPlus—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild …

AN Sari, A Elwakeel, JK Dhanjal, V Kumar, D Sundar… - Cancers, 2021 - mdpi.com
Simple Summary Functional inactivation of tumour suppressor protein p53 is frequently
found in a large variety of cancers. One of the mechanisms by which p53 is inactivated is …