Organismal aging exhibits wide-ranging hallmarks in divergent cell types across tissues,
organs, and systems. The advancement of single-cell technologies and generation of rich …

Current transcriptomics technologies, including bulk RNA-seq, single-cell RNA sequencing
(scRNA-seq), single-nucleus RNA-sequencing (snRNA-seq), and spatial transcriptomics …

Complex gene regulatory mechanisms underlie differentiation and reprogramming.
Contemporary single-cell lineage-tracing (scLT) methods use expressed, heritable DNA …

Aging is characterized by a decline in tissue function, but the underlying changes at cellular
resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a …

Conventional methods fall short in unraveling the dynamics of rare cell types related to
aging and diseases. Here we introduce EasySci, an advanced single-cell combinatorial …

The growing number of available single-cell gene expression datasets from different species
creates opportunities to explore evolutionary relationships between cell types across …

The origin and evolution of cell types has emerged as a key topic in evolutionary biology.
Driven by rapidly accumulating single-cell datasets, recent attempts to infer cell type …

Stem cells regulate their self-renewal and differentiation fate outcomes through both
symmetric and asymmetric divisions. m 6 A RNA methylation controls symmetric commitment …

Venezuelan equine encephalitis virus (VEEV) is an encephalitic alphavirus responsible for
epidemics of neurological disease across the Americas. Low-density lipoprotein receptor …

Drosophila hemocytes serve as the primary defense system against harmful threats,
allowing the animals to thrive. Hemocytes are often compared to vertebrate innate immune …