Abstract Anterior gradient 2 (AGR 2) is a dimeric protein disulfide isomerase family member
involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse …

Modern genomic studies, accumulation of biological information in repositories, plus novel
analytical and data-mining methodologies, comprise the backbone for the holistic …

Signal transducer and activator of transcription 3 (STAT3), a latent transcription factor
associated with inflammatory signaling and innate and adaptive immune responses, is …

Metagenomic analysis of environmental samples provides deep insight into the enzymatic
mixture of the corresponding niches, capable of revealing peptide sequences with novel …

Abstract Kallikrein-related peptidase 5 (KLK5) displays aberrant expression in cancer.
However, any functional association is missing. Here, we show that reconstitution of KLK5 …

Several studies have employed DNA microarrays to identify gene expression signatures that
mark human ageing; yet the features underlying this complicated phenomenon remain …

Schizophrenia affecting almost 1% and bipolar disorder affecting almost 3%–5% of the
global population constitute two severe mental disorders. The catecholaminergic and the …

Phage Display is a powerful method for the identification of peptide binding to targets of
variable complexities and tissues, from unique molecules to the internal surfaces of vessels …

Gene expression analysis, using high throughput genomic technologies, has become an
indispensable step for the meaningful interpretation of the underlying molecular complexity …

Bipolar disorder is a severe, lifelong psychiatric disease. The main underlying
pathophysiology of the disease is still incomprehensible. Various studies have suggested …