COVID‐19: Virology, biology and novel laboratory diagnosis

M Mohamadian, H Chiti, A Shoghli… - The journal of gene …, 2021 - Wiley Online Library
Background At the end of December 2019, a novel coronavirus tentatively named SARS‐
CoV‐2 in Wuhan, a central city in China, was announced by the World Health Organization …

[HTML][HTML] Comparative review of SARS-CoV-2, SARS-CoV, MERS-CoV, and influenza a respiratory viruses

Z Abdelrahman, M Li, X Wang - Frontiers in immunology, 2020 - frontiersin.org
The 2019 novel coronavirus (SARS-CoV-2) pandemic has caused a global health
emergency. The outbreak of this virus has raised a number of questions: What is SARS-CoV …

SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo

KPY Hui, JCW Ho, M Cheung, K Ng, RHH Ching, K Lai… - Nature, 2022 - nature.com
The emergence of SARS-CoV-2 variants of concern with progressively increased
transmissibility between humans is a threat to global public health. The Omicron variant of …

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

The COVID-19 pandemic: a comprehensive review of taxonomy, genetics, epidemiology, diagnosis, treatment, and control

YA Helmy, M Fawzy, A Elaswad, A Sobieh… - Journal of clinical …, 2020 - mdpi.com
A pneumonia outbreak with unknown etiology was reported in Wuhan, Hubei province,
China, in December 2019, associated with the Huanan Seafood Wholesale Market. The …

Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and …

KPY Hui, MC Cheung, RAPM Perera, KC Ng… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in
December 2019, causing a respiratory disease (coronavirus disease 2019, COVID-19) of …

Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia

DKW Chu, Y Pan, SMS Cheng, KPY Hui… - Clinical …, 2020 - academic.oup.com
Background A novel coronavirus of zoonotic origin (2019-nCoV) has recently been identified
in patients with acute respiratory disease. This virus is genetically similar to SARS …

[PDF][PDF] Lessons for COVID-19 immunity from other coronavirus infections

A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …

Middle East respiratory syndrome

ZA Memish, S Perlman, MD Van Kerkhove, A Zumla - The Lancet, 2020 - thelancet.com
Summary The Middle East respiratory syndrome coronavirus (MERS-CoV) is a lethal
zoonotic pathogen that was first identified in humans in Saudi Arabia and Jordan in 2012 …

Emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2: biology and therapeutic options

S Khan, R Siddique, MA Shereen, A Ali… - Journal of clinical …, 2020 - Am Soc Microbiol
The new decade of the 21st century (2020) started with the emergence of a novel
coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease …