Ascending neurons convey behavioral state to integrative sensory and action selection brain regions

CL Chen, F Aymanns, R Minegishi, VDV Matsuda… - Nature …, 2023 - nature.com
Knowing one's own behavioral state has long been theorized as critical for contextualizing
dynamic sensory cues and identifying appropriate future behaviors. Ascending neurons …

The functional organization of descending sensory-motor pathways in Drosophila

S Namiki, MH Dickinson, AM Wong, W Korff, GM Card - Elife, 2018 - elifesciences.org
In most animals, the brain controls the body via a set of descending neurons (DNs) that
traverse the neck. DN activity activates, maintains or modulates locomotion and other …

Comparative aspects of hearing in vertebrates and insects with antennal ears

JT Albert, AS Kozlov - Current Biology, 2016 - cell.com
The evolution of hearing in terrestrial animals has resulted in remarkable adaptations
enabling exquisitely sensitive sound detection by the ear and sophisticated sound analysis …

The fly brain atlas

LK Scheffer, IA Meinertzhagen - Annual Review of Cell and …, 2019 - annualreviews.org
The brain's synaptic networks endow an animal with powerfully adaptive biological
behavior. Maps of such synaptic circuits densely reconstructed in those model brains that …

[HTML][HTML] NBLAST: rapid, sensitive comparison of neuronal structure and construction of neuron family databases

M Costa, JD Manton, AD Ostrovsky, S Prohaska… - Neuron, 2016 - cell.com
Neural circuit mapping is generating datasets of tens of thousands of labeled neurons. New
computational tools are needed to search and organize these data. We present NBLAST, a …

Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body

MJ Dolan, S Frechter, AS Bates, C Dan, P Huoviala… - Elife, 2019 - elifesciences.org
Animals exhibit innate behaviours to a variety of sensory stimuli including olfactory cues. In
Drosophila, one higher olfactory centre, the lateral horn (LH), is implicated in innate …

A neural network for wind-guided compass navigation

TS Okubo, P Patella, I D'Alessandro, RI Wilson - Neuron, 2020 - cell.com
Spatial maps in the brain are most accurate when they are linked to external sensory cues.
Here, we show that the compass in the Drosophila brain is linked to the direction of the wind …

Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

GR Sterne, H Otsuna, BJ Dickson, K Scott - Elife, 2021 - elifesciences.org
Neural circuits carry out complex computations that allow animals to evaluate food, select
mates, move toward attractive stimuli, and move away from threats. In insects, the …

Auditory activity is diverse and widespread throughout the central brain of Drosophila

DA Pacheco, SY Thiberge, E Pnevmatikakis… - Nature …, 2021 - nature.com
Sensory pathways are typically studied by starting at receptor neurons and following
postsynaptic neurons into the brain. However, this leads to a bias in analyses of activity …

Functional maps of mechanosensory features in the Drosophila brain

P Patella, RI Wilson - Current Biology, 2018 - cell.com
Johnston's organ is the largest mechanosensory organ in Drosophila. It contributes to
hearing, touch, vestibular sensing, proprioception, and wind sensing. In this study, we used …