The development of multicellular organisms and the uniqueness of each cell are achieved
by distinct transcriptional programs. Multiple processes that regulate gene expression …

The understanding of the mechanisms that regulate gene expression to establish
differentiation programs and determine cell lineages, is one of the major challenges in …

Although the evolutionary history of the X chromosome indicates its specialization in male
fitness, its role in spermatogenesis has largely been unexplored. Currently only three X …

Female primordial germ cells (PGCs) undergo X chromosome reactivation (XCR) during
genome-wide reprogramming. XCR kinetics and dynamics are poorly understood at a …

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a de-ubiquitinating enzyme enriched in
neuronal and gonadal tissues known to regulate the cellular stores of mono-ubiquitin and …

The recognition of core promoter sequences by TFIID is the first step in RNA polymerase II
(Pol II) transcription initiation. Metazoan holo-TFIID is a trilobular complex, composed of the …

Myostatin is a crucial cytokine that is widely present in skeletal muscle and that negatively
regulates the growth and development of muscle cells. Recent research has shown that …

Prospermatogonia (ProSpg) link the embryonic development of male primordial germ cells
to the healthy establishment of postnatal spermatogonia and spermatogonial stem cells …

The cladoceran crustacean Daphnia has long been a model of energy allocation studies
due to its important position in the trophic cascade of freshwater ecosystems. However, the …

The recognition of core promoter sequences by the general transcription factor TFIID is the
first step in the process of RNA polymerase II (Pol II) transcription initiation. Metazoan holo …