[HTML][HTML] Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages

D Chen, X Zhang, Z Li, B Zhu - Theranostics, 2021 - ncbi.nlm.nih.gov
Macrophages phagocytize pathogens to initiate innate immunity and products from the
tumor microenvironment (TME) to mediate tumor immunity. The loss of tumor-associated …

Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases

P Kolkhir, D Elieh-Ali-Komi, M Metz… - Nature Reviews …, 2022 - nature.com
Mast cells have crucial roles in allergic and other inflammatory diseases. Preclinical
approaches provide circumstantial evidence for mast cell involvement in many diseases, but …

[HTML][HTML] Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome

LB Afrin, LB Weinstock, GJ Molderings - International journal of infectious …, 2020 - Elsevier
Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Landscape of mast cell populations across organs in mice and humans

M Tauber, L Basso, J Martin, L Bostan… - Journal of Experimental …, 2023 - rupress.org
Mast cells (MCs) are tissue-resident immune cells that exhibit homeostatic and neuron-
associated functions. Here, we combined whole-tissue imaging and single-cell RNA …

Siglecs as immune cell checkpoints in disease

S Duan, JC Paulson - Annual review of immunology, 2020 - annualreviews.org
Sialic acid–binding immunoglobulin-type lectins (Siglecs) are expressed on the majority of
white blood cells of the immune system and play critical roles in immune cell signaling …

[HTML][HTML] Inflammation and immunity in IPF pathogenesis and treatment

P Heukels, CC Moor, JH Von der Thüsen… - Respiratory …, 2019 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive, and ultimately fatal, chronic interstitial
lung disease characterized by enhanced extracellular matrix deposition. Repetitive alveolar …

New perspectives on the origins and heterogeneity of mast cells

AL St. John, APS Rathore, F Ginhoux - Nature Reviews Immunology, 2023 - nature.com
Mast cells are immune cells of the haematopoietic lineage that are now thought to have
multifaceted functions during homeostasis and in various disease states. Furthermore, while …

Cellular toxicity and immunological effects of carbon-based nanomaterials

X Yuan, X Zhang, L Sun, Y Wei, X Wei - Particle and fibre toxicology, 2019 - Springer
Background Carbon nanomaterials are a growing family of materials featuring unique
physicochemical properties, and their widespread application is accompanied by increasing …

Neutrophil migration in infection and wound repair: going forward in reverse

S De Oliveira, EE Rosowski… - Nature Reviews …, 2016 - nature.com
Neutrophil migration and its role during inflammation has been the focus of increased
interest in the past decade. Advances in live imaging and the use of new model systems …

Weaning stress and gastrointestinal barrier development: Implications for lifelong gut health in pigs

AJ Moeser, CS Pohl, M Rajput - Animal Nutrition, 2017 - Elsevier
The gastrointestinal (GI) barrier serves a critical role in survival and overall health of animals
and humans. Several layers of barrier defense mechanisms are provided by the epithelial …