Deregulations of the expression of the S100A8 and S100A9 genes and/or proteins, as well
as changes in their plasma levels or their levels of secretion in the bone marrow …

Since the discovery of circulating tumor cells in 1869, technological advances in studying
circulating biomarkers from patients' blood have made the diagnosis of nonhematologic …

Biomarkers are biological molecules found in body fluids or tissues, which can be
considered as indications of a normal or abnormal process, or of a condition or disease …

Background Acute lymphoblastic leukemia is the most common malignant cancer in
childhood. The signs and symptoms of childhood cancer are difficult to recognize, as it is not …

Background Cancer cachexia (CC) is linked to poor prognosis. Although the mechanisms
promoting this condition are not known, several circulating proteins have been proposed to …

Biomarkers are incorporated ubiquitously into clini-cal practice as surrogate endpoints of
physiologic and pathologic processes that cannot be measured directly. For example, a lipid …

Acute lymphoblastic leukemia (ALL) is the most common cancer in children and one of the
success stories in cancer therapeutics. Risk-directed therapy based on clinical, biologic and …

The available drug treatment options for adrenocortical carcinoma (ACC) are limited. In our
previous studies, the in vitro activity of 9-cis retinoic acid (9-cisRA) on adrenocortical NCI …

Simple Summary Acute lymphoblastic leukemia (ALL) is a hematological disease
characterized by the malfunction of the hematopoietic system. This process is generated and …

The maturation of B cells is a complex, multi-step process. During B cell differentiation,
errors can occur, leading to the emergence of aberrant versions of B cells that, finally …