Diabetes is a severe threat to global health. Almost 500 million people live with diabetes
worldwide. Most of them have type 2 diabetes (T2D). T2D patients are at risk of developing …

Pancreatic β-cell expansion and functional maturation during the birth-to-weaning period
plays an essential role in the adaptation of plasma insulin levels to metabolic needs. These …

Background: The need for minimally invasive biomarkers for the early diagnosis of type 2
diabetes (T2DM) prior to the clinical onset and monitoring of β-pancreatic cell loss is …

Tissue-specific gene methylation events are key to the pathogenesis of several diseases
and can be utilized for diagnosis and monitoring. Here, we established an in silico pipeline …

Background: Type 2 Diabetes Mellitus (T2DM) is a worldwide disorder as the most important
challenges of health-care systems. Controlling the normal glycaemia greatly profit long-term …

This study explored the effect of OPRM1 promoter region DNA methylation on the outcome
of treatment with the opioid antagonist naltrexone (NTX) for alcohol dependence (AD) …

Purpose Genetic factors have a role in response to a target medication (personalized
medicine). This study aimed to review available evidence about the relationship between …

Diabetes has become a pandemic as the number of diabetic people continues to rise
globally. Being a heterogeneous disease, it has different manifestations and associated …

Recently, a large number of studies have been conducted to investigate the variability of
response in the treatment of diabetes mellitus (T2DM), which make personalized medicine …

Аннотация В последнее время проводится большое количество исследований,
направленных на изучение вариабельности ответа при лечении cахарного диабета 2 …