Physical activity can treat and prevent depressive symptoms, but its antidepressant
mechanisms are yet to be established. In this review, we comprehensively assess key …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

Background Exercise is a promising nonpharmacological therapy for cognitive dysfunction,
but it is unclear which type of exercise is most effective. The objective of this study was to …

Exercise plays a key role in healthy aging by promoting both physical and cognitive function.
Physical function and cognitive function appear to be interrelated and may share common …

Hippocampal volume increase in response to aerobic exercise has been consistently
observed in animal models. However, the evidence from human studies is equivocal. We …

Background This meta-analysis of randomized controlled trials (RCTs) examines the efficacy
of physical exercise as treatment for unipolar depression, both as an independent …

Exercise is a non-pharmacological strategy to mitigate the deleterious effects of aging on
brain health. However, a large amount of variation exists in its efficacy. Sex of participants …

The current pandemic was caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2). The quarantine period during corona virus disease 19 (COVID-19) outbreak …

The human brain adapts to changing demands by altering its functional and structural
properties (“neuroplasticity”) which results in learning and acquiring skills. Convergent …

No medications prevent or reverse age-related cognitive decline. Physical activity (PA)
enhances memory in rodents, but findings are mixed in human studies. As a result, exercise …