Identifying vulnerable brain networks in mouse models of genetic risk factors for late onset Alzheimer's disease
A Badea, W Wu, J Shuff, M Wang… - Frontiers in …, 2019 - frontiersin.org
The major genetic risk for late onset Alzheimer's disease has been associated with the
presence of APOE4 alleles. However, the impact of different APOE alleles on the brain aging …
presence of APOE4 alleles. However, the impact of different APOE alleles on the brain aging …
Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer's Disease
Spatial navigation and orientation are emerging as promising markers for altered cognition
in prodromal Alzheimer's disease, and even in cognitively normal individuals at risk for …
in prodromal Alzheimer's disease, and even in cognitively normal individuals at risk for …
Feature attention graph neural network for estimating brain age and identifying important neural connections in mouse models of genetic risk for Alzheimer's disease
HS Moon, A Mahzarnia, J Stout, RJ Anderson… - Imaging …, 2024 - direct.mit.edu
Abstract Alzheimer's disease (AD), a widely studied neurodegenerative disorder, poses
significant research challenges due to its high prevalence and complex etiology. Age, a …
significant research challenges due to its high prevalence and complex etiology. Age, a …
Optimizing diffusion imaging protocols for structural connectomics in mouse models of neurological conditions
RJ Anderson, CM Long, ED Calabrese… - Frontiers in …, 2020 - frontiersin.org
Network approaches provide sensitive biomarkers for neurological conditions, such as
Alzheimer's disease (AD). Mouse models can help advance our understanding of underlying …
Alzheimer's disease (AD). Mouse models can help advance our understanding of underlying …
Brain network fingerprints of Alzheimer's disease risk factors in mouse models with humanized APOE alleles
S Winter, A Mahzarnia, RJ Anderson, ZY Han… - Magnetic Resonance …, 2024 - Elsevier
Alzheimer's disease (AD) presents complex challenges due to its multifactorial nature,
poorly understood etiology, and late detection. The mechanisms through which genetic and …
poorly understood etiology, and late detection. The mechanisms through which genetic and …
APOE, Immune Factors, Sex, and Diet Interact to Shape Brain Networks in Mouse Models of Aging
S Winter, A Mahzarnia, RJ Anderson, ZY Han… - bioRxiv, 2023 - biorxiv.org
Alzheimer's disease (AD) presents complex challenges due to its multifactorial nature,
poorly understood etiology, and late detection. The mechanisms through which genetic …
poorly understood etiology, and late detection. The mechanisms through which genetic …
Absolute Winding Number Differentiates Spatial Navigation Strategies with Genetic Risk for Alzheimer's Disease
Spatial navigation and orientation are emerging as promising markers for altered cognition
in prodromal Alzheimer's disease, and even in cognitively normal individuals at risk for …
in prodromal Alzheimer's disease, and even in cognitively normal individuals at risk for …
Microcephaly with altered cortical layering in GIT1 deficiency revealed by quantitative neuroimaging
A Badea, R Schmalzigaug, W Kim, P Bonner… - Magnetic resonance …, 2021 - Elsevier
Abstract G Protein-Coupled Receptor Kinase-Interacting Protein-1 (GIT1) regulates neuronal
functions, including cell and axon migration and synapse formation and maintenance, and …
functions, including cell and axon migration and synapse formation and maintenance, and …
Genetic Substrates of Brain Vulnerability and Resilience in Aging APOE2 Mice
A Mahzarnia, HS Moon, J Stout, RJ Anderson, M Strain… - bioRxiv, 2022 - biorxiv.org
The interplay between genotype, age, and sex may play an important role in determining
successful versus pathological aging. Predicting brain networks vulnerable to age …
successful versus pathological aging. Predicting brain networks vulnerable to age …
[PDF][PDF] Genetic Substrates of Brain Vulnerability and Resilience in APOE2 Mice Transitioning from Midlife to Old Age
A Mahzarnia, HS Moon, J Stout, RJ Anderson, M Strain… - scholar.archive.org
The interplay between genotype, age, and sex may play an important role in determining
successful versus pathological aging. Predicting brain networks vulnerable to age …
successful versus pathological aging. Predicting brain networks vulnerable to age …