Gastric cancer (GC) remains the fifth most prevalent cancer worldwide and the third leading
cause of global cancer mortality. Comprehensive‐omic studies have unveiled a …

The single-layered, simple epithelium of the gastro-intestinal tract controls nutrient uptake,
coordinates our metabolism and shields us from pathogens. Despite its seemingly simple …

In vitro cancer cultures, including three-dimensional organoids, typically contain exclusively
neoplastic epithelium but require artificial reconstitution to recapitulate the tumor …

Purpose: The tumor microenvironment (TME) consists of a heterogenous cellular milieu that
can influence cancer cell behavior. Its characteristics have an impact on treatments such as …

Background High-grade serous tubo-ovarian cancer (HGSTOC) is characterised by
extensive inter-and intratumour heterogeneity, resulting in persistent therapeutic resistance …

Purpose: The liver is the most frequent metastatic site for colorectal cancer. Its
microenvironment is modified to provide a niche that is conducive for colorectal cancer cell …

Gastric cancer is one of the most serious malignant tumor and threatens the health of people
worldwide. Its heterogeneity leaves many clinical problems unsolved. To treat it effectively …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the coronavirus
disease 2019 (COVID-19), has provoked more than six million deaths worldwide and …

Human intestinal epithelial cells form a primary barrier protecting us from pathogens, yet
only limited knowledge is available about individual contribution of each cell type to …

Although immunotherapy has revolutionized solid tumor treatment, durable responses in
gastric cancer (GC) remain limited. The heterogeneous tumor microenvironment (TME) …