Recent insights on anti-dengue virus (DENV) medicinal plants: review on in vitro, in vivo and in silico discoveries

SYM Lim, JY Chieng, Y Pan - All Life, 2021 - Taylor & Francis
Dengue has become a global affliction despite continuous efforts to find cure for this age-old
disease. Hopeful results for dengue vaccine are far-fetched as the effectiveness are tied to …

Green Nano‐Biotechnology: A New Sustainable Paradigm to Control Dengue Infection

T Zohra, AT Khalil, F Saeed, B Latif… - Bioinorganic …, 2022 - Wiley Online Library
Dengue is a growing mosquito‐borne viral disease prevalent in 128 countries, while 3.9
billion people are at high risk of acquiring the infection. With no specific treatment available …

Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus

M Tahir ul Qamar, A Maryam, I Muneer, F Xing… - Scientific reports, 2019 - nature.com
Emergence of Dengue as one of the deadliest viral diseases prompts the need for
development of effective therapeutic agents. Dengue virus (DV) exists in four different …

MPD3: a useful medicinal plants database for drug designing

A Mumtaz, UA Ashfaq, MT ul Qamar… - Natural product …, 2017 - Taylor & Francis
Medicinal plants are the main natural pools for the discovery and development of new drugs.
In the modern era of computer-aided drug designing (CADD), there is need of prompt efforts …

An in-silico investigation of phytochemicals as antiviral agents against dengue fever

CN Powers, WN Setzer - Combinatorial chemistry & high …, 2016 - ingentaconnect.com
A virtual screening analysis of our library of phytochemical structures with dengue virus
protein targets has been carried out using a molecular docking approach. A total of 2194 …

Chemistry of protein-phenolic interactions toward the microbiota and microbial infections

H Yilmaz, B Gultekin Subasi, HU Celebioglu… - Frontiers in …, 2022 - frontiersin.org
Along with health concerns, interest in plants as food and bioactive phytochemical sources
has been increased in the last few decades. Phytochemicals as secondary plant metabolites …

Antiviral activity of astragaloside II, astragaloside III and astragaloside IV compounds against dengue virus: computational docking and in vitro studies

P Indu, N Arunagirinathan, MR Rameshkumar… - Microbial …, 2021 - Elsevier
This study was aimed to identify the phytocompounds possessing anti-dengue virus activity
using in silico and in vitro approaches. A total of 7000 phytocompounds were virtually …

Structure activity relationship (SAR) and quantitative structure activity relationship (QSAR) studies showed plant flavonoids as potential inhibitors of dengue NS2B …

MW Sarwar, A Riaz, SMR Dilshad, A Al-Qahtani… - BMC structural …, 2018 - Springer
Background Due to dengue virus disease, half of the world population is at severe health
risk. Viral encoded NS2B-NS3 protease complex causes cleavage in the nonstructural …

Investigating the molecular mechanism of staphylococcal DNA gyrase inhibitors: A combined ligand-based and structure-based resources pipeline

S Durdagi, MT ul Qamar, RE Salmas, Q Tariq… - Journal of Molecular …, 2018 - Elsevier
Appropriate therapeutic solutions against Staphylococcal infections are currently limited. To
work out the complex task of challenging drug resistance in Staphylococcus aureus, new …

In-silico identification and evaluation of plant flavonoids as dengue NS2B/NS3 protease inhibitors using molecular docking and simulation approach

MT ul Qamar, UA Ashfaq, K Tusleem… - Pakistan journal of …, 2017 - go.gale.com
Dengue infection is prevailing among the people not only from the developing countries but
also from the developed countries due to its high morbidity rate around the globe. Hence …