Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Background Neuraminidase inhibitors (NIs) are stockpiled and recommended by public
health agencies for treating and preventing seasonal and pandemic influenza. They are …

Background Influenza is an important cause of morbidity and mortality worldwide. Treatment
options are scarce, and new drugs with novel mechanisms of action are needed. We aimed …

Long‐term care facility environments and the vulnerability of their residents provide a setting
conducive to the rapid spread of influenza virus and other respiratory pathogens. Infections …

Most pharmaceutical products are manufactured either by applying a total synthesis
approach or by modifying a naturally occurring product. In both cases, a wide range of …

Influenza is a long-standing health problem. For treatment of seasonal flu and possible
pandemic infections, there is a need to develop new anti-influenza drugs that have good …

Black elder (Sambucus nigra L.) has a long ethnobotanical history across many disparate
cultures as a treatment for viral infection and is currently one of the most‐used medicinal …

Objectives To update a 2005 Cochrane review that assessed the effects of neuraminidase
inhibitors in preventing or ameliorating the symptoms of influenza, the transmission of …

Background Appendectomy, the surgical removal of the appendix, is performed primarily for
acute appendicitis. Patients who undergo appendectomy for complicated appendicitis …