Importance Hereditary factors play a key role in the risk of developing several cancers.
Identification of a germline predisposition can have important implications for treatment …

Identifying individuals with hereditary syndromes allows for improved cancer surveillance,
risk reduction, and optimized management. Establishing criteria for assessment allows for …

The liberal use of upper endoscopy has led to an increased detection of gastric and
duodenal polyps, which are identified in as many as 6 and 4.6% of patient examinations …

Abstract Purpose of Review Colorectal cancer (CRC) is the third most common cancer in the
USA and inherited cancer syndromes are responsible for approximately 3–5% of all CRCs …

Background & Aims Hereditary factors play a role in the development of colorectal cancer
(CRC). Identification of germline predisposition can have implications on treatment and …

Importance Personalized surveillance, prophylaxis, and cancer treatment options for
individuals with hereditary cancer predisposition are informed by results of germline genetic …

Inherited pathogenic variants account for 5% to 10% of all breast cancer (BC) and colorectal
cancer (CRC) cases. Here, we sought to profile the pathogenic variants in 25 cancer …

Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide.
Hereditary CRC syndromes account for approximately 5–10% of all CRC, with a lifetime risk …

Abstract Background Primary Extra‐mammary Paget's disease (EMPD) is a very rare
cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a …

Simple Summary Despite recent advances in early diagnostic and therapeutic strategies,
colorectal cancer remains one of the most diagnosed and lethal cancers worldwide. Further …