Mechanisms of isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review

X Zhuang, L Li, T Liu, R Zhang, P Yang… - Frontiers in …, 2022 - frontiersin.org
Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment,
and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct …

Bioactive Components and Biological Activities of Crocus sativus L. Byproducts: A Comprehensive Review

Y Wu, Y Gong, J Sun, Y Zhang, Z Luo… - Journal of Agricultural …, 2023 - ACS Publications
The production of saffron spice results in numerous byproducts, as only 15 g of spice can be
produced from 1 kg of flowers, indicating that over 90% of the saffron flower material is …

Plant growth promoting and antifungal asset of indigenous rhizobacteria secluded from saffron (Crocus sativus L.) rhizosphere

A Rasool, MI Mir, M Zulfajri, MM Hanafiah… - Microbial …, 2021 - Elsevier
Saffron (Crocus sativus L.) is an important plant in medicine. The Kashmir Valley (J&K, India)
is one of the world's largest and finest saffron producing regions. However, over the past …

The genus Crocus L.: A review of ethnobotanical uses, phytochemistry and pharmacology

L Mohtashami, MS Amiri, M Ramezani… - Industrial Crops and …, 2021 - Elsevier
Crocus L. is a genus of perennial plants in the family Iridaceae. Numerous research
regarding healing effects of Crocus spp. on human diseases are being published worldwide …

Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular …

M Scuto, S Modafferi, F Rampulla, V Zimbone… - Mechanisms of Ageing …, 2022 - Elsevier
Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

[HTML][HTML] An overview of analytical methods employed for quality assessment of Crocus sativus (saffron)

S Eghbali, F Farhadi, VR Askari - Food Chemistry: X, 2023 - Elsevier
This paper reviews qualitative and quantitative analytical methodologies used for the
appraisal of saffron quality, as the most expensive spice. Due to the chemical diversity of …

Antioxidant, Antimicrobial, Antidiabetic and Cytotoxic Activity of Crocus sativus L. Petals

AF Wali, HAA Alchamat, HK Hariri, BK Hariri… - Applied Sciences, 2020 - mdpi.com
The purpose of this research is to examine in vitro antioxidant, antimicrobial, antidiabetic
and cytotoxic efficacy of different extracts of Crocus sativus L. petals. Antioxidant activity of …

Potential Nutraceutical Benefits of In Vivo Grown Saffron (Crocus sativus L.) As Analgesic, Anti-inflammatory, Anticoagulant, and Antidepressant in Mice

A Khan, NA Muhamad, H Ismail, A Nasir, AAK Khalil… - Plants, 2020 - mdpi.com
Crocus sativus, a medicinally important herbaceous plant, has been traditionally used to
cure coughs, colds, insomnia, cramps, asthma, and pain. Moreover, the therapeutic …

Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model

C Orabona, E Orecchini, C Volpi, F Bacaloni, E Panfili… - Pharmaceutics, 2022 - mdpi.com
The dried stigmas of Crocus sativus L.(Iridaceae) are traditionally processed to produce
saffron, a spice widely used as a food coloring and flavoring agent, which is important in the …

[HTML][HTML] Deciphering the emerging role of phytocompounds: Implications in the management of drug-resistant tuberculosis and ATDs-induced hepatic damage

MA Ansari, S Shoaib, MN Alomary, H Ather… - Journal of Infection and …, 2023 - Elsevier
Tuberculosis is a disease of poverty, discrimination, and socioeconomic burden.
Epidemiological studies suggest that the mortality and incidence of tuberculosis are …