Primary biliary cirrhosis

C Selmi, CL Bowlus, ME Gershwin, RL Coppel - The Lancet, 2011 - thelancet.com
Primary biliary cirrhosis is a chronic liver disease characterised by intrahepatic bile-duct
destruction, cholestasis, and, in some cases, cirrhosis. Evidence supporting the autoimmune …

Genetics and geoepidemiology of primary biliary cirrhosis: following the footprints to disease etiology

C Selmi, P Invernizzi, M Zuin, M Podda… - Seminars in Liver …, 2005 - thieme-connect.com
The etiopathogenesis of primary biliary cirrhosis (PBC), an autoimmune disease
characterized by the progressive destruction of intrahepatic bile ducts, is still enigmatic …

From bases to basis: linking genetics to causation in primary biliary cirrhosis

P Invernizzi, C Selmi, IR MacKay, M Podda… - Clinical …, 2005 - Elsevier
Primary biliary cirrhosis (PBC) is a multifactorial autoimmune disease with inherited and
environmental components in pathogenesis. It is exceptional among autoimmune diseases …

Autoimmune hepatitis type 2 associated with an unexpected and transient presence of primary biliary cirrhosis-specific antimitochondrial antibodies: a case study and …

P Invernizzi, MG Alessio, DS Smyk, A Lleo… - BMC …, 2012 - Springer
Background Unlike other autoimmune liver diseases, primary biliary cirrhosis (PBC) has
never been reported in early childhood, while type 2 autoimmune hepatitis (AIH) is …

[PDF][PDF] Single‐nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary …

Y Ohishi, M Nakamura, N Iio, S Higa, M Inayoshi… - …, 2008 - Wiley Online Library
Primary biliary cirrhosis (PBC) is a multifactorial disease in which genetic factors rather than
environmental factors may predominantly contribute to the pathogenesis. In order to identify …

Genes and (auto) immunity in primary biliary cirrhosis

C Selmi, P Invernizzi, M Zuin, M Podda, MF Seldin… - Genes & …, 2005 - nature.com
Primary biliary cirrhosis (PBC) is a chronic autoimmune cholestatic liver disease most
commonly encountered in postmenopausal women; it is characterized by high-titer serum …

熊去氧胆酸联合维生素D 治疗PBC 患者疗效和外周血T 淋巴细胞亚群的变化

刘映川, 赵鹏程, 游亭, 邓红英, 薛江凤 - 实用肝脏病杂志, 2018 - manu43.magtech.com.cn
目的研究应用维生素D 辅助熊去氧胆酸(UDCA) 治疗原发性胆汁性肝硬化(PBC)
患者的疗效及其对血清25-羟基维生素D3 (25-(OH) 2-D3) 和外周血T 淋巴细胞亚群的影响 …

T‐cell receptor beta polymorphism is not associated with endometriosis

P Tripputi, M Bignotto, D Cigognini… - Journal of Obstetrics …, 2011 - Wiley Online Library
Aim: We carried out an association study between T‐cell receptor beta polymorphism
(TCRB) and endometriosis to investigate the difference in allelic frequency. Polymorphisms …

A possible mechanism for non‐replication of allelic association between a single nucleotide polymorphism of the human beta T‐cell receptor and autoimmune …

P Tripputi, S Bianchi, L Fedele - International Journal of …, 2008 - Wiley Online Library
Gene polymorphisms, in particular single nucleotide polymorphisms (SNPs), have been
associated to multifactorial diseases such as cancer, inflammation and autoimmunity …

Sex-Related Differences in Allelic Frequency of the Human Beta T Cell Receptor SNP rs1800907: A Retrospective Analysis from Milan Metropolitan Area

EM Varoni, G Lodi, M Del Fabbro, A Sardella… - Vaccines, 2021 - mdpi.com
This paper aims at retrospectively re-analyzing the different distribution, between males and
females, in the allelic frequency of the human β T cell receptor (TCR β) single nucleotide …