Roles of podoplanin in malignant progression of tumor

H Suzuki, MK Kaneko, Y Kato - Cells, 2022 - mdpi.com
Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor
development and normal development of the lung, kidney, and lymphatic vascular systems …

[HTML][HTML] A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models

T Tanaka, H Suzuki, T Ohishi, MK Kaneko, Y Kato - Cells, 2024 - mdpi.com
Podoplanin (PDPN) overexpression is associated with poor clinical outcomes in various
tumors. PDPN is involved in malignant tumor progression by promoting invasiveness and …

Multifaceted approach toward mapping out the anticancer properties of small molecules via in vitro evaluation on melanoma and nonmelanoma skin cancer cells, and …

ST Boateng, T Roy, ME Agbo… - Chemical Biology & …, 2024 - Wiley Online Library
Melanoma and nonmelanoma skin cancers are among the most prevalent and most lethal
forms of skin cancers. To identify new lead compounds with potential anticancer properties …

[HTML][HTML] Scalable recurrence graph network for stratifying RhoB texture dynamics in rectal cancer biopsies

TD Pham - APL Machine Learning, 2025 - pubs.aip.org
The scalable recurrence graph network (SRGNet) is introduced in this paper to improve the
accuracy of predicting five-year survival outcomes in rectal cancer patients by analyzing …

The nicotinamide ruthenium (II) complex induces the production of reactive oxygen species (ROS), cell cycle arrest, and apoptosis in melanoma cells

HVR Silva, GAF da Silva, B Zavan, RP Machado… - Polyhedron, 2023 - Elsevier
A set of new ruthenium complexes,[RuCl (NIC)(dppb)(4, 4′-Me-bipy)] PF 6 (C1),[RuCl
(NIC)(dppb)(4, 4′-Methoxy-bipy)] PF 6 (C2), and [RuCl (NIC)(dppb)(5, 5′-Me-bipy)] PF 6 …

ARHGEF3 Regulates Hair Follicle Morphogenesis

K Kalyanakrishnan, A Beaudin, A Jetté… - …, 2024 - pmc.ncbi.nlm.nih.gov
During embryogenesis, cells arrange into precise patterns that enable tissues and organs to
develop specialized functions. Despite its critical importance, the molecular choreography …

Development of Functionalized Synthetic Small Molecules as Novel Skin Anticancer Agents

ST Boateng - 2023 - search.proquest.com
Skin cancer (SC), comprising non-melanoma skin cancer and cutaneous melanoma, is the
most prevalent form of cancer in the United States, with a significant financial burden …

Role of the cytoskeleton in melanogenesis

B ZANON - thesis.unipd.it
This thesis presents a critical analysis of the scientific article entitled “PRP4 Promotes Skin
Cancer by Inhibiting Production of Melanin, Blocking Influx of Extracellular Calcium, and …