Complexity of life sciences in quantum and AI era

A Pyrkov, A Aliper, D Bezrukov… - Wiley …, 2024 - Wiley Online Library
Having made significant advancements in understanding living organisms at various levels
such as genes, cells, molecules, tissues, and pathways, the field of life sciences is now …

The synergy between neuroscience and control theory: the nervous system as inspiration for hard control challenges

MS Madhav, NJ Cowan - Annual Review of Control, Robotics …, 2020 - annualreviews.org
Here, we review the role of control theory in modeling neural control systems through a top-
down analysis approach. Specifically, we examine the role of the brain and central nervous …

INFEKTA—An agent-based model for transmission of infectious diseases: The COVID-19 case in Bogotá, Colombia

J Gomez, J Prieto, E Leon, A Rodríguez - PloS one, 2021 - journals.plos.org
The transmission dynamics of the coronavirus—COVID-19—have challenged humankind at
almost every level. Currently, research groups around the globe are trying to figure out such …

[HTML][HTML] On Markov blankets and hierarchical self-organisation

ER Palacios, A Razi, T Parr, M Kirchhoff… - Journal of theoretical …, 2020 - Elsevier
Biological self-organisation can be regarded as a process of spontaneous pattern formation;
namely, the emergence of structures that distinguish themselves from their environment …

[HTML][HTML] The constrained disorder principle defines living organisms and provides a method for correcting disturbed biological systems

Y Ilan - Computational and Structural Biotechnology Journal, 2022 - Elsevier
The constrained disorder principle defines the existence and function of living organisms.
The principle specifies that biological systems comprise a disorder within constrained …

Why is Complexity Science valuable for reaching the goals of the UN 2030 Agenda?

PL Gentili - Rendiconti Lincei. Scienze fisiche e naturali, 2021 - Springer
The goals and targets included in the 2030 Agenda compiled by the United Nations want to
stimulate action in areas of critical importance for humanity and the Earth. These goals and …

[HTML][HTML] Redefining roles: A paradigm shift in tryptophan–kynurenine metabolism for innovative clinical applications

M Tanaka, Á Szabó, L Vécsei - International Journal of Molecular …, 2024 - mdpi.com
The tryptophan–kynurenine (KYN) pathway has long been recognized for its essential role
in generating metabolites that influence various physiological processes. Traditionally, these …

A decade of thermostatted kinetic theory models for complex active matter living systems

C Bianca - Physics of Life Reviews, 2024 - Elsevier
In the last decade, the thermostatted kinetic theory has been proposed as a general
paradigm for the modeling of complex systems of the active matter and, in particular, in …

[HTML][HTML] Parallel and hierarchical neural mechanisms for adaptive and predictive behavioral control

T Macpherson, M Matsumoto, H Gomi, J Morimoto… - Neural Networks, 2021 - Elsevier
Our brain can be recognized as a network of largely hierarchically organized neural circuits
that operate to control specific functions, but when acting in parallel, enable the performance …

INFEKTA: a general agent-based model for transmission of infectious diseases: studying the COVID-19 propagation in Bogotá-Colombia

J Gomez, J Prieto, E Leon, A Rodriguez - MedRxiv, 2020 - medrxiv.org
The transmission dynamics of the coronavirus-COVID-19-have challenged humankind at
almost every level. Currently, research groups around the globe are trying to figure out such …