Neutrophil extracellular traps—the dark side of neutrophils
OE Sørensen, N Borregaard - The Journal of clinical …, 2016 - Am Soc Clin Investig
Neutrophil extracellular traps (NETs) were discovered as extracellular strands of
decondensed DNA in complex with histones and granule proteins, which were expelled …
decondensed DNA in complex with histones and granule proteins, which were expelled …
[HTML][HTML] Understanding the role of neutrophils in chronic inflammatory airway disease
Airway neutrophilia is a common feature of many chronic inflammatory lung diseases and is
associated with disease progression, often regardless of the initiating cause. Neutrophils …
associated with disease progression, often regardless of the initiating cause. Neutrophils …
[HTML][HTML] Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease
AJ Dicker, ML Crichton, EG Pumphrey… - Journal of Allergy and …, 2018 - Elsevier
Background Neutrophil extracellular traps (NETs) have been observed in the airway in
patients with chronic obstructive pulmonary disease (COPD), but their clinical and …
patients with chronic obstructive pulmonary disease (COPD), but their clinical and …
Simvastatin improves neutrophil function and clinical outcomes in pneumonia. A pilot randomized controlled clinical trial
Rationale: Population studies suggest improved sepsis outcomes with statins, but the results
of randomized controlled trials in patients with sepsis and organ dysfunction in critical care …
of randomized controlled trials in patients with sepsis and organ dysfunction in critical care …
Neutrophil extracellular trap production in patients with colorectal cancer in vitro
JJR Richardson, C Hendrickse… - International journal …, 2017 - Wiley Online Library
Purpose. Neutrophil Extracellular Traps (NETs) are extracellular neutrophil derived DNA
webs which have been implicated in cancer progression and in the development of …
webs which have been implicated in cancer progression and in the development of …
[HTML][HTML] Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target
MJ Hughes, HM McGettrick… - European Respiratory …, 2020 - Eur Respiratory Soc
Multimorbidity is increasingly common and current healthcare strategies are not always
aligned to treat this complex burden of disease. COPD, type-2 diabetes mellitus (T2D) and …
aligned to treat this complex burden of disease. COPD, type-2 diabetes mellitus (T2D) and …
The regulation of neutrophil migration in patients with sepsis: the complexity of the molecular mechanisms and their modulation in sepsis and the heterogeneity of …
Ø Bruserud, KA Mosevoll, Ø Bruserud, H Reikvam… - Cells, 2023 - mdpi.com
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Common causes include gram-negative and gram-positive bacteria as …
response to infection. Common causes include gram-negative and gram-positive bacteria as …
Vitamin D deficiency in human and murine sepsis
Objectives: Vitamin D deficiency has been implicated as a pathogenic factor in sepsis and
ICU mortality but causality of these associations has not been demonstrated. To determine …
ICU mortality but causality of these associations has not been demonstrated. To determine …
Neutrophil extracellular traps in respiratory disease: guided anti-microbial traps or toxic webs?
B Cortjens, JBM van Woensel, RA Bem - Paediatric respiratory reviews, 2017 - Elsevier
Neutrophil recruitment to the airways and lungs is a major hallmark of many respiratory
diseases. One of the more recently discovered unique innate immune effector mechanisms …
diseases. One of the more recently discovered unique innate immune effector mechanisms …