Many Gram-negative bacteria use the sophisticated type II secretion system (T2SS) to
translocate a wide range of proteins from the periplasm across the outer membrane. The …

Prokaryotes have engineered sophisticated surface nanomachines that have allowed them
to colonize Earth and thrive even in extreme environments. Filamentous machineries …

Type II protein secretion systems (T2SS) are molecular machines that promote specific
transport of folded periplasmic proteins in Gram-negative bacteria, across a dedicated …

The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

abstract Gram-negative bacteria use the type II secretion system to transport a large number
of secreted proteins from the periplasmic space into the extracellular environment. Many of …

Summary Type IV pili (T4P) are bacterial virulence factors involved in a wide variety of
functions including deoxyribonucleic acid uptake, surface attachment, biofilm formation and …

The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …

Motility and protein secretion are key processes contributing to bacterial virulence. A wealth
of phylogenetic, biochemical and structural evidence support the hypothesis that the widely …

Gram-negative bacteria translocate various proteins including virulence factors across their
outer membrane via type 2 secretion systems (T2SSs). T2SSs are thought to contain a …

The type II secretion system (T2SS) is a multiprotein envelope-spanning assembly that
translocates a wide range of virulence factors, enzymes and effectors through the outer …